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[巴拉那州西北部地区孕妇中HIV、乙型肝炎、弓形虫病和风疹血清学阳性的患病率]

[Prevalence of positive sorology for HIV, hepatitis B, toxoplasmosis and rubella in pregnant women from the northwestern region of the state of Paraná].

作者信息

Ferezin Rafael Isolani, Bertolini Dennis Armando, Demarchi Izabel Galhardo

机构信息

Programa de Pós-graduação de Biociências Aplicadas à Farmácia, Universidade Estadual de Maringá, Maringá, PR, Brasil.

出版信息

Rev Bras Ginecol Obstet. 2013 Feb;35(2):66-70. doi: 10.1590/s0100-72032013000200005.

Abstract

PURPOSE

To ascertain the seroprevalence of human immunodeficiency virus (HIV), hepatitis B (HBV), toxoplasmosis and rubella infections in pregnant women in northwestern Paraná.

METHODS

We conducted a retrospective study based on the results of serological screening during prenatal care of 1,534 patients during the first half of 2010. We included only results from the first prenatal exam and with a simultaneous search for IgG and IgM antibodies to rubella and toxoplasmosis. Serology was performed by microparticle enzyme immunoassay (MEIA). Data were analyzed statistically by the χ² test, with the level of significance set at 5%.

RESULTS

HIV positivity was 0.3%, positivity of HBV serology (HbsAg) was 0.5%, reactivity to IgM antibodies to Toxoplasma gondii was 1.1%, and reactivity to IgG antibodies was 59.0%. For rubella, no patient was positive for IgM, and IgG reactivity was 99.6%. Data analysis showed no statistical association between seroprevalence and patient age, except for the frequency of anti-T. gondii IgG, which was higher in the 30 to 44 year age group.

CONCLUSION

The prevalence of these infectious diseases in pregnant women from northwestern Paraná is comparable to that observed in other regions of Brazil.

摘要

目的

确定巴拉那州西北部孕妇中人类免疫缺陷病毒(HIV)、乙型肝炎(HBV)、弓形虫病和风疹感染的血清流行率。

方法

我们基于2010年上半年1534例患者产前检查期间的血清学筛查结果进行了一项回顾性研究。我们仅纳入首次产前检查的结果,并同时检测风疹和弓形虫病的IgG和IgM抗体。血清学检测采用微粒酶免疫测定法(MEIA)。数据采用χ²检验进行统计学分析,显著性水平设定为5%。

结果

HIV阳性率为0.3%,HBV血清学(HbsAg)阳性率为0.5%,弓形虫IgM抗体反应性为1.1%,IgG抗体反应性为59.0%。对于风疹,没有患者IgM呈阳性,IgG反应性为99.6%。数据分析显示,血清流行率与患者年龄之间无统计学关联,但抗弓形虫IgG频率除外,该频率在30至44岁年龄组中较高。

结论

巴拉那州西北部孕妇中这些传染病的流行率与巴西其他地区观察到的情况相当。

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