Catalysis Research Laboratory (CaRLa) Im Neuenheimer Feld 584, 69120 Heidelberg, Germany.
Organic Synthesis, BASF SE Carl-Bosch-Str. 38, 67056 Ludwigshafen, Germany.
Chem Commun (Camb). 2020 Jun 2;56(44):5977-5980. doi: 10.1039/d0cc01533d.
The reaction of cyclic amides with acetylene under low pressure, using ruthenium-phosphine catalysts, afforded a broad variety of N-vinylated amides including (azabicyclic) lactams, oxazolidinones, benzoisoxazolones, isoindolinones, quinoxalinones, oxazinanones, cyclic urea derivatives (imidazolidinones), nucleobases (thymine), amino acid anhydrides and thiazolidinone.
在低压下，使用钌-膦催化剂，环状酰胺与乙炔反应，得到了广泛的 N-乙烯基酰胺，包括（氮杂环丁烷）内酰胺、恶唑烷酮、苯并异噁唑酮、异吲哚啉酮、喹喔啉酮、恶唑烷酮、环状脲衍生物（咪唑烷酮）、核碱基（胸腺嘧啶）、氨基酸酐和噻唑烷酮。
