Thiene Gaetano, Basso Cristina, Cozza Andrea, Zanatta Alberto
Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Italy.
Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Italy; Cardiovascular Pathology Unit - Azienda Ospedaliera di Padova, Italy.
Int J Cardiol. 2020 Oct 15;317:81-85. doi: 10.1016/j.ijcard.2020.04.076. Epub 2020 Apr 27.
The existence of an intrinsic electrical platform in the heart, taking over the impulse formation and transmission, is a relatively recent discovery. Leonardo Da Vinci in 1510 wrote that the heart is self-moving. Harvey in 1628 observed that the cardiac movement is seen to begin from the auricles. Purkinje in 1839 discovered at the microscope a network of large, pale muscular cells in the ventricles. His in 1893 showed a muscle bundle connecting the atrial to the ventricular septum. Tawara in 1906 found a node at the atrial origin of His bundle. Finally, Keith and Flack observed a structure of primitive muscular fibres at the sino-atrial junction, where "the dominating rhythm of the heart is believed to normally arise".
心脏中存在一个内在的电平台，负责冲动的形成和传导，这是一个相对较新的发现。1510年，列奥纳多·达·芬奇写道，心脏是自我运动的。1628年，哈维观察到心脏运动始于心房。1839年，浦肯野在显微镜下发现心室中有一个由大型、浅色肌细胞组成的网络。1893年，希斯发现一束肌肉连接心房和心室间隔。1906年，塔瓦拉在希氏束的心房起源处发现一个结。最后，基思和弗拉克在窦房交界处观察到一种原始肌纤维结构，据信“心脏的主导节律通常在此产生”。
