Silverman Mark E, Hollman Arthur
The Fuqua Heart Center of Piedmont Hospital and the Department of Medicine of Emory University, Atlanta, Georgia, USA.
Heart. 2007 Oct;93(10):1184-7. doi: 10.1136/hrt.2006.105049.
In 1839, Jan Evangelista Purkinje discovered a net of gelatinous fibres in the subendocardium of the heart. Walter Gaskell in the 1880s observed that the impulse of the heart began in the sinus venosus, and that this region had the most rhythmic ability. A conducting bundle between the atrium and the ventricle was found by Wilhelm His, Jr in 1893. In 1906, Sunao Tawara found a "complex knoten" of tissue at the proximal end of the His bundle. He concluded that this was the inception of an electrical conducting system which continued from the AV node through the bundle of His, divided into the bundle branches, and terminated as the Purkinje fibres. The collaboration of Arthur Keith and Martin Flack led to discovery of the sinus node, finalising the discovery of the electrical system of the heart and providing an anatomical answer to the baffling mystery: "Why does the heart beat?"
1839年,扬·伊万格利斯塔·浦肯野在心脏的心内膜下层发现了一层凝胶状纤维网。19世纪80年代,沃尔特·加斯克尔观察到心脏的冲动始于静脉窦,且该区域具有最强的节律性。1893年,小威廉·希斯发现了心房和心室之间的传导束。1906年,田原直男在希氏束近端发现了一个组织“复合结”。他得出结论,这是一个电传导系统的起始点,该系统从房室结开始,通过希氏束延续,分为束支,并以浦肯野纤维结束。亚瑟·基思和马丁·弗拉克的合作促成了窦房结的发现,最终完成了心脏电系统的发现,并为这个令人困惑的谜团提供了一个解剖学答案:“心脏为什么跳动?”