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2
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本文引用的文献

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THE SINO-AURICULAR NODE: A HISTORICAL NOTE.窦房结:历史记录
Br Heart J. 1942 Jul;4(3):77-9. doi: 10.1136/hrt.4.3.77.
2
The story of the atrioventricular bundle with remarks concerning embryonic heart activity.房室束的故事及关于胚胎心脏活动的评论。
J Hist Med Allied Sci. 1949;4(3):319-33. doi: 10.1093/jhmas/iv.3.319.
3
The Form and Nature of the Muscular Connections between the Primary Divisions of the Vertebrate Heart.脊椎动物心脏主要分区之间肌肉连接的形式与本质
J Anat Physiol. 1907 Apr;41(Pt 3):172-89.
4
On the Innervation of the Heart, with especial reference to the Heart of the Tortoise.论心脏的神经支配,特别提及龟的心脏
J Physiol. 1883 Aug;4(2-3):43-230.14. doi: 10.1113/jphysiol.1883.sp000121.
5
Why does the heart beat? The discovery of the electrical system of the heart.心脏为何跳动?心脏电系统的发现。
Circulation. 2006 Jun 13;113(23):2775-81. doi: 10.1161/CIRCULATIONAHA.106.616771.
6
The auriculo-ventricular bundle of the human heart. 1906.人类心脏的房室束。1906年。
Ann Noninvasive Electrocardiol. 2004 Oct;9(4):400-9. doi: 10.1111/j.1542-474X.2004.94003.x.
7
Walter Gaskell and the understanding of atrioventricular conduction and block.沃尔特·加斯克尔与房室传导和阻滞的理解
J Am Coll Cardiol. 2002 May 15;39(10):1574-80. doi: 10.1016/s0735-1097(02)01839-9.
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Sunao Tawara: a father of modern cardiology.田原纯:现代心脏病学之父。
Pacing Clin Electrophysiol. 2001 Jan;24(1):88-96. doi: 10.1046/j.1460-9592.2001.00088.x.
9
The origin of the heart beat: a tale of frogs, jellyfish, and turtles.心跳的起源:青蛙、水母和海龟的故事。
Circulation. 1987 Sep;76(3):493-500. doi: 10.1161/01.cir.76.3.493.
10
Jan Evangelista Purkinje (Purkinĕ).扬·伊万杰利斯塔·浦肯野(浦肯涅)。
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基思和弗莱克发现窦房结:纪念他们1907年发表成果一百周年

Discovery of the sinus node by Keith and Flack: on the centennial of their 1907 publication.

作者信息

Silverman Mark E, Hollman Arthur

机构信息

The Fuqua Heart Center of Piedmont Hospital and the Department of Medicine of Emory University, Atlanta, Georgia, USA.

出版信息

Heart. 2007 Oct;93(10):1184-7. doi: 10.1136/hrt.2006.105049.

DOI:10.1136/hrt.2006.105049
PMID:17890694
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2000948/
Abstract

In 1839, Jan Evangelista Purkinje discovered a net of gelatinous fibres in the subendocardium of the heart. Walter Gaskell in the 1880s observed that the impulse of the heart began in the sinus venosus, and that this region had the most rhythmic ability. A conducting bundle between the atrium and the ventricle was found by Wilhelm His, Jr in 1893. In 1906, Sunao Tawara found a "complex knoten" of tissue at the proximal end of the His bundle. He concluded that this was the inception of an electrical conducting system which continued from the AV node through the bundle of His, divided into the bundle branches, and terminated as the Purkinje fibres. The collaboration of Arthur Keith and Martin Flack led to discovery of the sinus node, finalising the discovery of the electrical system of the heart and providing an anatomical answer to the baffling mystery: "Why does the heart beat?"

摘要

1839年,扬·伊万格利斯塔·浦肯野在心脏的心内膜下层发现了一层凝胶状纤维网。19世纪80年代,沃尔特·加斯克尔观察到心脏的冲动始于静脉窦,且该区域具有最强的节律性。1893年,小威廉·希斯发现了心房和心室之间的传导束。1906年,田原直男在希氏束近端发现了一个组织“复合结”。他得出结论,这是一个电传导系统的起始点,该系统从房室结开始,通过希氏束延续,分为束支,并以浦肯野纤维结束。亚瑟·基思和马丁·弗拉克的合作促成了窦房结的发现,最终完成了心脏电系统的发现,并为这个令人困惑的谜团提供了一个解剖学答案:“心脏为什么跳动?”