Neonatal Intensive Care Unit, Department of Neonatology, Bambino Gesù Children's Hospital, IRCCS, Piazza S. Onofrio 4, 00165, Rome, Italy.
Division of Neonatology, St-Luc University Hospital, Catholic University of Louvain, 1200, Brussels, Belgium.
Ital J Pediatr. 2020 Apr 29;46(1):56. doi: 10.1186/s13052-020-0820-x.
Recently, an outbreak of viral pneumonitis in Wuhan, Hubei, China successively spread as a global pandemia, led to the identification of a novel betacoronavirus species, the 2019 novel coronavirus, successively designated 2019-nCoV then SARS-CoV-2). The SARS-CoV-2 causes a clinical syndrome designated coronavirus disease 2019 (COVID19) with a spectrum of manifestations ranging from mild upper respiratory tract infection to severe pneumonitis, acute respiratory distress syndrome (ARDS) and death. Few cases have been observed in children and adolescents who seem to have a more favorable clinical course than other age groups, and even fewer in newborn babies. This review provides an overview of the knowledge on SARS-CoV-2 epidemiology, transmission, the associated clinical presentation and outcomes in newborns and infants up to 6 months of life.
最近，中国湖北省武汉市病毒性肺炎的爆发相继蔓延成为全球大流行，导致一种新型β冠状病毒种的鉴定，即 2019 年新型冠状病毒，先后被指定为 2019-nCoV，然后是 SARS-CoV-2）。SARS-CoV-2 引起一种临床综合征，称为 2019 年冠状病毒病（COVID19），其表现谱从轻度上呼吸道感染到严重肺炎、急性呼吸窘迫综合征（ARDS）和死亡不等。在儿童和青少年中观察到的病例较少，他们的临床病程似乎比其他年龄组更有利，在新生儿中则更少。这篇综述提供了 SARS-CoV-2 在流行病学、传播、与临床表现和结局相关的知识概述，这些知识涉及到 6 个月以下的新生儿和婴儿。
