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[新型冠状病毒肺炎患儿的多系统炎症综合征:风湿病学视角]

[Multisystemic inflammatory syndrome in children with COVID-19: a rheumatology perspective].

作者信息

Naranjo Arango Yonatan Andrés, Farfán Cortés Abraham Yamit Amin Ariff, García Henao Juan Pablo, Arango Slingsby Christine, Saldarriaga Rivera Lina María

机构信息

Grupo de Investigación en Medicina Interna, Programa de Medicina, Facultad de Ciencias de la Salud, Universidad Tecnológica de Pereira, Pereira, Colombia.

Programa de Medicina, Facultad de Ciencias de la Salud, Universidad Tecnológica de Pereira, Pereira, Colombia.

出版信息

Rev Colomb Reumatol. 2021 Oct-Dec;28(4):289-299. doi: 10.1016/j.rcreu.2020.09.005. Epub 2020 Oct 17.

Abstract

The coronavirus disease 2019 (COVID-19) produced by SARS-CoV-2 has taken on great importance in recent months, and is under constant investigation by different areas of medicine, including rheumatology, in search of the best evidence scientific. In the case of the paediatric population, it is particularly important as it was first thought that the impact of the pandemic in this population would be less due to the low presence of severe cases. Evidence is now being reported of clinical pictures in children with a diagnosis of COVID-19 who are characterised by an altered inflammatory state consisting of a storm of pro-inflammatory cytokines that produces manifestations similar to those presented in autoimmune diseases, such as Kawasaki disease. It has been called Multisystemic Inflammatory Syndrome in children, temporarily associated with SARS-CoV-2 which, in many cases requires hospitalisation in paediatric intensive care units and multidisciplinary management by various specialties.

摘要

严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引发的2019冠状病毒病(COVID-19)在最近几个月变得极为重要,包括风湿病学在内的不同医学领域都在持续对其进行研究,以寻找最佳的科学证据。对于儿科人群而言,这一点尤为重要,因为最初人们认为大流行对该人群的影响较小,原因是重症病例较少。现在有证据表明,被诊断为COVID-19的儿童会出现临床症状,其特征是炎症状态改变,表现为促炎细胞因子风暴,会产生与自身免疫性疾病(如川崎病)相似的症状。它被称为儿童多系统炎症综合征,暂时与SARS-CoV-2相关,在许多情况下需要入住儿科重症监护病房并由多个专科进行多学科管理。

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Clinical manifestations of children with COVID-19: A systematic review.新冠病毒病患儿的临床表现:一项系统综述
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