Contreras-Escámez Beatriz, Izquierdo Mikel, Galbete Jiménez Arkaitz, Gutiérrez-Valencia Marta, Cedeno-Veloz Bernardo A, Martínez-Velilla Nicolás
Servicio de Geriatría, Complejo Hospitalario de Navarra, Pamplona, Navarra, España; Navarrabiomed-Departamento de Salud-Universidad Pública de Navarra, Pamplona, España.
Universidad Pública de Navarra, IDISNA, Pamplona, Navarra, España; CIBER of Frailty and Healthy Aging, Instituto de Salud Carlos III, Madrid, España.
Med Clin (Barc). 2020 Jul 10;155(1):18-22. doi: 10.1016/j.medcli.2020.01.028. Epub 2020 Apr 27.
There are multiple frailty detection tools, but they have not been specifically developed for the institutionalised population. The aim of this study is to ascertain at 3-year follow-up which tool predicts functional impairment and mortality most precisely.
Longitudinal cohort study with 110 patients in Pamplona (Navarra)>65 years. Four frailty tools were applied (Fried Criteria, Rockwood Frailty Scale, FRAIL-NH and Imputed Fried Frailty Criteria). The power of the association between the scales and the results was assessed by linear regression and Cox's analyses.
46.5% of the sample died during time to follow-up, 68% of whom died in their nursing home, with 43-month mean survival. Of the studied population, 71.3% showed disability at 3 years, especially the frail subjects. The robust patients had longer hospitalizations (m=3.4 days) than the frail. Imputed Fried and FRAIL-NH found statistically significant differences between groups for the variables studied. Imputed Fried Frailty Criteria showed a significant HR of death for the frail subjects (HR=3.3).
The Imputed Fried and FRAIL-NH tools showed a higher predictive capability for functional and cognitive decline, but only the Imputed Fried Frailty Criteria found a significant relationship between frailty and mortality.
有多种衰弱检测工具，但它们并非专门为机构化人群开发。本研究的目的是在3年随访期确定哪种工具能最准确地预测功能损害和死亡率。
对潘普洛纳（纳瓦拉）110名65岁以上患者进行纵向队列研究。应用了四种衰弱工具（弗里德标准、罗克伍德衰弱量表、FRAIL-NH和推算弗里德衰弱标准）。通过线性回归和考克斯分析评估量表与结果之间关联的强度。
随访期间46.5%的样本死亡，其中68%在养老院死亡，平均生存43个月。在研究人群中，71.3%在3年时出现残疾，尤其是衰弱受试者。健康的患者住院时间（中位数=3.4天）比衰弱患者长。推算弗里德标准和FRAIL-NH在所研究变量的组间发现了统计学显著差异。推算弗里德衰弱标准显示衰弱受试者的死亡风险比显著（风险比=3.3）。
推算弗里德标准和FRAIL-NH工具对功能和认知衰退显示出更高的预测能力，但只有推算弗里德衰弱标准发现衰弱与死亡率之间存在显著关系。
