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在一项为期 4 周的随机交叉研究中,açai(Euterpe oleracea Mart.)和juçara(Euterpe edulis Mart.)果汁可提高健康成年人的高密度脂蛋白胆固醇水平和抗氧化防御能力。

Açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study.

机构信息

Nutrition Post-Graduate Program, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil.

Nutrition Post-Graduate Program, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil; Department of Clinical Analysis, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil.

出版信息

Clin Nutr. 2020 Dec;39(12):3629-3636. doi: 10.1016/j.clnu.2020.04.007. Epub 2020 Apr 11.

DOI:10.1016/j.clnu.2020.04.007
PMID:32349893
Abstract

OBJECTIVE

To evaluate the effects of moderate-term açaí and juçara juice intake on fasting glucose, lipid profile, and oxidative stress biomarkers in healthy subjects.

METHODS

A randomized cross-over study was performed with 30 healthy adults. The subjects were assigned to drink 200 mL/day of açaí or juçara juice for four weeks with a 4-week washout period. Before and after each nutritional intervention, blood samples were obtained to evaluate the outcomes: fasting glucose, total cholesterol, triglycerides, high-density lipoprotein-cholesterol (HDL-c), low-density lipoprotein-cholesterol (LDL-c), small, dense LDL-c (sd-LDL-c), total antioxidant capacity (TAC), total oxidant status (TOS), oxidative stress index (OSI), uric acid, and activity of the enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx).

RESULTS

After four weeks, açaí and juçara juices increased the concentrations of HDL-c by 7.7% and 11.4%, respectively (P < 0.05). In addition, açaí juice intake promoted significant increases in TAC (66.7%), CAT (275.1%), GPx (15.3%), and a decrease in OSI (55.7%) compared to baseline (P < 0.05 for all). Juçara juice intake significantly increased CAT activity (~15.0%) in relation to baseline. No significant intergroup differences were observed for any outcomes (P > 0.05).

CONCLUSION

The results indicated a positive impact of regular consumption of açaí and juçara juices on the HDL-c levels, as well as on the antioxidant enzyme activities, which may contribute to cardiovascular health.

摘要

目的

评估中等剂量的阿萨伊和巴尔沙果果汁摄入对健康受试者空腹血糖、血脂谱和氧化应激生物标志物的影响。

方法

一项随机交叉研究纳入了 30 名健康成年人。受试者被分配每天饮用 200 毫升阿萨伊或巴尔沙果果汁,持续四周,然后进行为期四周的洗脱期。在每个营养干预前后,采集血样以评估以下结果:空腹血糖、总胆固醇、甘油三酯、高密度脂蛋白胆固醇(HDL-c)、低密度脂蛋白胆固醇(LDL-c)、小而密 LDL-c(sd-LDL-c)、总抗氧化能力(TAC)、总氧化状态(TOS)、氧化应激指数(OSI)、尿酸以及超氧化物歧化酶(SOD)、过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GPx)的活性。

结果

四周后,阿萨伊和巴尔沙果果汁分别使 HDL-c 浓度增加了 7.7%和 11.4%(P<0.05)。此外,与基线相比,阿萨伊果汁摄入可显著增加 TAC(66.7%)、CAT(275.1%)、GPx(15.3%),并降低 OSI(55.7%)(所有 P 值均<0.05)。与基线相比,巴尔沙果果汁摄入可使 CAT 活性显著增加(约 15.0%)。各组间在任何结果上均无显著差异(P>0.05)。

结论

研究结果表明,经常饮用阿萨伊和巴尔沙果果汁对 HDL-c 水平以及抗氧化酶活性具有积极影响,这可能有助于心血管健康。

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