Moffa Antonio, Rinaldi Vittorio, Mantovani Mario, Pierri Michelangelo, Fiore Valeria, Costantino Andrea, Pignataro Lorenzo, Baptista Peter, Cassano Michele, Casale Manuele
Department of Otolaryngology, University of Foggia, Foggia, Italy.
Integrated Sleep Surgery Team UCBM, Unit of Otolaryngology, Integrated Therapies in Otolaryngology, Campus Bio-Medico University, Rome, Italy.
Sleep Breath. 2020 Sep;24(3):1115-1127. doi: 10.1007/s11325-020-02088-z. Epub 2020 Apr 29.
The use of barbed sutures (BS) for the treatment of retropalatal collapse and vibration in patients suffering from snoring and obstructive sleep apnea (OSA) has significantly increased in the last few years. Many surgeons have discovered the advantages and unique properties of the BS and allowed the popular surgical pharyngoplasty techniques to be updated and improved.
A systematic review was performed to identify all the clinical studies concerning the different barbed pharyngoplasty (BP) techniques used for the treatment of palatal collapse in snoring and OSA patients. A qualitative analysis of data extracted was conducted.
We included 12 studies of which 10 are prospective and 2 retrospective: 9 single-arm studies on the efficacy of a specific BP technique, 1 randomized clinical trial on the comparison between BP and control groups, and 2 studies on the correlation between two different BP techniques. To date, in the literature, 5 different types of BP techniques have been described: barbed snore surgery, barbed reposition pharyngoplasty, barbed expansion sphincter pharyngoplasty, barbed suture suspension, and barbed soft palate posterior webbing flap pharyngoplasty. All the studies showed an overall improvement in the primary efficacy parameters investigated (apnea-hypopnea index, oxygen desaturation index, and Epworth sleepiness scale) in each of the surgical techniques performed without any major complications.
Given the extreme heterogeneity of the studies analyzed, it is necessary to perform more randomized and control studies on large samples aimed to define the best BP technique based on its effectiveness, surgical success rate, patient's compliance, and complications.
在过去几年中,倒刺缝线(BS)用于治疗打鼾和阻塞性睡眠呼吸暂停(OSA)患者的腭后塌陷和振动的情况显著增加。许多外科医生发现了倒刺缝线的优点和独特特性,使得流行的外科咽成形术技术得以更新和改进。
进行了一项系统综述,以确定所有关于用于治疗打鼾和OSA患者腭塌陷的不同倒刺咽成形术(BP)技术的临床研究。对提取的数据进行了定性分析。
我们纳入了12项研究,其中10项为前瞻性研究,2项为回顾性研究:9项关于特定BP技术疗效的单臂研究,1项关于BP组与对照组比较的随机临床试验,以及2项关于两种不同BP技术之间相关性的研究。迄今为止,文献中已描述了5种不同类型的BP技术:倒刺打鼾手术、倒刺复位咽成形术、倒刺扩张括约肌咽成形术、倒刺缝线悬吊术和倒刺软腭后蹼瓣咽成形术。所有研究均表明,在每种所实施的手术技术中,所研究的主要疗效参数(呼吸暂停低通气指数、氧饱和度下降指数和爱泼华嗜睡量表)总体上有所改善,且无任何重大并发症。
鉴于所分析研究的极端异质性,有必要进行更多针对大样本的随机对照研究,旨在根据其有效性、手术成功率、患者依从性和并发症来确定最佳的BP技术。