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倒刺悬吊咽成形术治疗阻塞性睡眠呼吸暂停低通气综合征患者的咽侧壁和腭部塌陷

Barbed suspension pharyngoplasty for treatment of lateral pharyngeal wall and palatal collapse in patients affected by OSAHS.

作者信息

Barbieri Marco, Missale Francesco, Incandela Fabiola, Fragale Marco, Barbieri Andrea, Roustan Valeria, Canevari Frank Rikki, Peretti Giorgio

机构信息

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Department of Otorhinolaryngology, Head and Neck Surgery, University of Genoa, Genoa, Italy.

出版信息

Eur Arch Otorhinolaryngol. 2019 Jun;276(6):1829-1835. doi: 10.1007/s00405-019-05426-4. Epub 2019 Apr 16.

Abstract

PURPOSE

The aim of this study is to analyze the efficacy of a new modified pharyngoplasty technique with barbed sutures: barbed suspension pharyngoplasty (BSP).

METHODS

We enrolled patients affected by obstructive sleep apnea-hypopnea syndrome (OSAHS), having the main site of obstruction at the palatal and lateral pharyngeal walls, who refused or failed to tolerate CPAP therapy and underwent non-resective pharyngoplasty with barbed sutures between January 2014 and October 2017. Two surgical techniques with barbed sutures were used: barbed reposition pharyngoplasty (BRP) and BSP; the main characteristics of the latter are a double passage of the needle, each side, through the soft palate.

RESULTS

Forty-two patients met the study inclusion criteria and were included in the analysis. Twenty-two patients underwent BRP and 20 BSP. Patients treated with both BRP and BSP achieved significant improvement in polysomnographic parameters: AHI, ODI, t90%, and daily sleepiness tested by the ESS questionnaire (p < 0.001). There were no significant differences between groups considering gender, age, or severity of OSAHS (p > 0.05). Outcomes were also comparable (p = 0.10) in the two groups; patients who underwent BSP had successful treatment in 100% of cases, compared to 86% with BRP, with a cure rate of 40% vs. 18%.

CONCLUSIONS

BSP is a novel surgical technique that is effective in treating oropharyngeal collapse and can be tailored for patients with high collapsibility of the soft palate who might benefit from the palatal stiffness given by multiple passages of the suture inside it.

摘要

目的

本研究旨在分析一种采用倒刺缝线的改良咽成形术新技术——倒刺悬吊咽成形术(BSP)的疗效。

方法

我们纳入了受阻塞性睡眠呼吸暂停低通气综合征(OSAHS)影响、主要阻塞部位在腭部和咽侧壁、拒绝或不耐受持续气道正压通气(CPAP)治疗且在2014年1月至2017年10月期间接受了采用倒刺缝线的非切除性咽成形术的患者。使用了两种带倒刺缝线的手术技术:倒刺复位咽成形术(BRP)和BSP;后者的主要特点是针在软腭两侧各穿两次。

结果

42例患者符合研究纳入标准并纳入分析。22例患者接受了BRP,20例接受了BSP。接受BRP和BSP治疗的患者在多导睡眠图参数方面均有显著改善:呼吸暂停低通气指数(AHI)、氧减指数(ODI)、t90%以及通过Epworth嗜睡量表(ESS)问卷测试的每日嗜睡程度(p < 0.001)。在考虑性别、年龄或OSAHS严重程度时,两组之间无显著差异(p > 0.05)。两组的结果也具有可比性(p = 0.10);接受BSP的患者100%治疗成功,而接受BRP的患者为86%,治愈率分别为40%和18%。

结论

BSP是一种治疗口咽塌陷有效的新型手术技术,可针对软腭高塌陷性的患者进行调整,这些患者可能受益于缝线在软腭内多次穿行所带来的腭部硬度。

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