Ogata M, Nakasono I, Iwasaki M, Kubo S, Suyama H, Narita K, Tsukazaki T, Muta I
Department of Legal Medicine, Nagasaki University School of Medicine, Japan.
Hum Hered. 1988;38(5):303-7. doi: 10.1159/000153803.
Two familial cases in which the saliva Lea levels were seen to dissociate with the donors' red blood cell (RBC) Lewis types are reported. In case 1, the saliva from a donor with an RBC type of Le(a+b-) contained a low level of Lea antigen. A low Lea level was also observed in the saliva from this proband's father who has an RBC type of Le(a+b-). In case 2, the saliva from a donor with an RBC type of Le(a-b+) contained a high level of Lea antigen. High Lea levels were also present in the saliva of this proband's father and brothers with an RBC type of Le(a-b+).
报告了两例家族性病例,其中观察到唾液中Lea水平与供体红细胞(RBC)Lewis血型相分离。在病例1中,一名RBC血型为Le(a+b-)的供体的唾液中Lea抗原水平较低。该先证者的父亲RBC血型为Le(a+b-),其唾液中也观察到低水平的Lea。在病例2中,一名RBC血型为Le(a-b+)的供体的唾液中含有高水平的Lea抗原。该先证者的父亲和兄弟RBC血型为Le(a-b+),其唾液中也存在高水平的Lea。