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激光屈光手术对屈光参差性弱视眼优势眼的调节作用。

The Modulation of Laser Refractive Surgery on Sensory Eye Dominance of Anisometropia.

作者信息

Liu Hongting, Chen Qi, Lan Fangfang, Luo Yan, Lin Enwei, Luo Wuqiang, Kong Ming, Wang Jiangxia, Zhang Fengju

机构信息

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology &Visual Sciences Key Lab, Beijing 100730, China.

Guangxi Optometry and Visual Science Center, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China.

出版信息

J Ophthalmol. 2020 Mar 27;2020:3873740. doi: 10.1155/2020/3873740. eCollection 2020.

Abstract

PURPOSE

To evaluate the effect of laser refractive surgery on sensory eye dominance of anisometropia.

METHODS

A total of 156 subjects with nonanisometropic myopia and 70 subjects with anisometropic myopia were enrolled in the first part of the study. The dichoptic motion coherence threshold technique was applied to collect the normal dataset and distribution of sensory eye dominance. The second part of the study included 40 subjects with nonanisometropic myopia and 40 subjects with anisometropic myopia who received the femtosecond laser-assisted keratomileusis (Fs-LASIK). A comprehensive ophthalmologic evaluation was performed with particular attention to sensory eye dominance preoperatively and one-week and one-month postoperatively. The ocular dominance index (ODI) was applied to evaluate the subject's overall degree of sensory ocular dominance. Visual acuity, sighting eye dominance, and stereo acuity were also accessed.

RESULTS

In experiment one, the mean ODI in the nonanisometropic group and the anisometropic group was 1.48 ± 0.63 and 1.95 ± 1.07, respectively. The ODI values of the anisometropic group were significantly higher than those of the nonanisometropic group (Mann-Whitney test, < 0.001). The demographics information and the distribution of ODI values in both groups are summarized in tables and figures. In experiment two, all LASIK procedures were uneventful and no postoperative complications were observed during the postoperative follow-up. Preoperatively, the ODI values of the anisometropic LASIK group were significantly higher than those of the nonanisometropic LASIK group, which was consistent with the results of part 1. However, one week after operation, the mean ODI values of the anisometropic LASIK group had significantly decreased from 1.89 ± 1.09 to 1.39 ± 0.44. And, the mean ODI values slightly increased to 1.65 ± 0.61 one-month postoperatively. In the nonanisometropic LASIK group, there were no statistically significant differences of ODI changes among preoperative, post-one-week and post-one-month visits. The demographics information and the changes of ODI of both LASIK groups are summarized in tables and figures.

CONCLUSION

Stronger sensory eye dominance is seen in the subjects with anisometropic myopia compared to subjects with nonanisometropic myopia. The strong sensory dominance of anisometropia becomes more balanced at one week of postoperation but returns to the preoperative level after one month. Laser refractive surgery had a short-term modulation of sensory eye dominance.

摘要

目的

评估激光屈光手术对屈光参差性近视患者感觉眼优势的影响。

方法

研究的第一部分纳入了156例非屈光参差性近视患者和70例屈光参差性近视患者。采用双眼运动相干阈值技术收集正常数据集及感觉眼优势的分布情况。研究的第二部分纳入了40例接受飞秒激光原位角膜磨镶术(Fs-LASIK)的非屈光参差性近视患者和40例屈光参差性近视患者。术前、术后1周和1个月进行全面的眼科评估,特别关注感觉眼优势。应用眼优势指数(ODI)评估受试者感觉眼优势的总体程度。同时还评估了视力、注视眼优势和立体视锐度。

结果

在实验一中,非屈光参差组和屈光参差组的平均ODI分别为1.48±0.63和1.95±1.07。屈光参差组的ODI值显著高于非屈光参差组(Mann-Whitney检验,P<0.001)。两组的人口统计学信息和ODI值分布情况在表格和图表中进行了总结。在实验二中,所有LASIK手术均顺利完成,术后随访期间未观察到术后并发症。术前,屈光参差性LASIK组的ODI值显著高于非屈光参差性LASIK组,这与第一部分的结果一致。然而,术后1周,屈光参差性LASIK组的平均ODI值从1.89±1.09显著降至1.39±0.44。术后1个月,平均ODI值略有升高,至1.65±0.61。在非屈光参差性LASIK组中,术前、术后1周和术后1个月的ODI变化无统计学显著差异。两个LASIK组的人口统计学信息和ODI变化情况在表格和图表中进行了总结。

结论

与非屈光参差性近视患者相比,屈光参差性近视患者的感觉眼优势更强。屈光参差的强烈感觉优势在术后1周变得更加平衡,但术后1个月又恢复到术前水平。激光屈光手术对感觉眼优势有短期调节作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c213/7152944/b9a9e9dec993/JOPH2020-3873740.001.jpg

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