Huang Kaiyan, Xia Mi, Gong Qianwen, Li Kexin, Xu Yijie, Wang Hui, Wang Yuzhou, Zhou Jiawei, Hu Liang
National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, People's Republic of China.
State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, People's Republic of China.
Invest Ophthalmol Vis Sci. 2025 Apr 1;66(4):32. doi: 10.1167/iovs.66.4.32.
The purpose of this study was to investigate the relationship between binocular imbalance and myopic shift in unoperated eyes after unilateral small incision lenticule extraction (SMILE) and transepithelial photorefractive keratectomy (tPRK) procedures.
This study included 51 participants who had undergone unilateral SMILE (n = 28) or tPRK (n = 23) for at least 3 months. The participants were categorized into stable and myopic shift groups based on the difference between preoperative and postoperative spherical equivalent refractive (SER) errors of unoperated eyes. Psychophysical tests were conducted only at the postoperative follow-up point. Spatial sensory eye dominance was determined by analyzing a binocular orientation combination task at spatial frequencies of 1 and 6 cycles per degree (c/d). A rotating cylinder generated a spontaneous Pulfrich phenomenon to determine the interocular delay at spatial frequencies of 0.95 and 2.95 c/d.
The logrBP in the myopic shift group was significantly more negative than in the stable group at 1 c/d (P < 0.01) and 6 c/d (P < 0.01). And logrBP correlated with the difference between preoperative and postoperative SER of the unoperated eye at 1 c/d (rs = 0.513, P < 0.001) and 6 c/d (rs = 0.504, P < 0.001). In the myopic shift group, logrBP was more negative at 6 c/d than at 1 c/d (P = 0.013), but not in the stable group.
Patients who experience myopic shift in the unoperated eye after unilateral SMILE or tPRK tend to have stronger sensory eye dominance in that eye, with a more pronounced dominance at higher spatial frequencies.
本研究旨在探讨单眼小切口飞秒透镜切除术（SMILE）和经上皮准分子激光角膜切削术（tPRK）术后，未手术眼的双眼不平衡与近视漂移之间的关系。
本研究纳入了51例接受单眼SMILE（n = 28）或tPRK（n = 23）手术至少3个月的参与者。根据未手术眼术前和术后等效球镜屈光（SER）误差的差异，将参与者分为稳定组和近视漂移组。仅在术后随访时进行心理物理学测试。通过分析每度1和6周/度（c/d）空间频率下的双眼定向组合任务来确定空间感觉眼优势。使用旋转圆柱体产生自发的普尔弗里希现象，以确定0.95和2.95 c/d空间频率下的双眼延迟。
近视漂移组在1 c/d（P < 0.01）和6 c/d（P < 0.01）时的logrBP显著低于稳定组。并且logrBP在1 c/d（rs = 0.513，P < 0.001）和6 c/d（rs = 0.504，P < 0.001）时与未手术眼术前和术后SER的差异相关。在近视漂移组中，6 c/d时的logrBP比1 c/d时更负（P = 0.013），但在稳定组中并非如此。
单侧SMILE或tPRK术后未手术眼出现近视漂移的患者，该眼往往具有更强的感觉眼优势，且在较高空间频率下优势更明显。
