Changes and correlations of antioxidant enzymes, lipid peroxidation and serum neutral lipids due to haemodialysis treatment in chronic uraemic patients.

A study was made of the changes in the activities of the antioxidant enzymes superoxide dismutase and catalase in the blood of chronic uraemic patients before and after haemodialysis. Changes in serum lipids (primarily neutral lipids), lipoproteins and lipid peroxidation were also followed. Before haemodialysis, antioxidant enzyme activities decreased, while lipid peroxidation increased both in the plasma and in the RBC haemolysates. Quantitative changes in the lipids increased the risk factors. Haemodialysis moderated these risk factors and a tendency to improvement was observed.