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急性前庭综合征和听力损失酷似迷路炎,作为多发性硬化的初始表现。

Acute vestibular syndrome and hearing loss mimicking labyrinthitis as initial presentation of multiple sclerosis.

作者信息

Valente Pedro, Pinto Isabel, Aguiar Cristina, Castro Eugénia, Condé Artur, Larangeiro João

机构信息

Department of Otorhinolaryngology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Rua Conceição Fernandes, S/n, 4434-502, Vila Nova de Gaia, Porto, Portugal.

Department of Otorhinolaryngology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Rua Conceição Fernandes, S/n, 4434-502, Vila Nova de Gaia, Porto, Portugal.

出版信息

Int J Pediatr Otorhinolaryngol. 2020 Jul;134:110048. doi: 10.1016/j.ijporl.2020.110048. Epub 2020 Apr 21.

DOI:10.1016/j.ijporl.2020.110048
PMID:32353617
Abstract

Acute vestibular syndrome is most often caused by vestibular neuritis or stroke, although demyelinating diseases may be responsible for 4% of all AVS episodes. The authors present the case of a previously healthy 17-year-old female patient complaining of spontaneous vertigo and right-sided hearing loss. Otoneurological examination suggested a peripheral vestibular cause and video head impulse test revealed a reduced vestibulo-ocular reflex gain. The presence of sensorineural hearing loss raised the suspicion of a central cause and prompted imaging evaluation. A brain MRI evidenced demyelinating lesions in the right middle cerebellar peduncle and the patient was ultimately diagnosed with Multiple Sclerosis.

摘要

急性前庭综合征最常见的病因是前庭神经炎或中风,不过脱髓鞘疾病可能导致4%的急性前庭综合征发作。作者报告了一例先前健康的17岁女性患者的病例,该患者主诉自发性眩晕和右侧听力丧失。耳神经学检查提示为外周前庭病因,视频头脉冲试验显示前庭眼反射增益降低。感音神经性听力损失的存在引发了对中枢病因的怀疑,并促使进行影像学评估。脑部磁共振成像显示右侧小脑中脚有脱髓鞘病变,该患者最终被诊断为多发性硬化症。

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Developing a Diagnostic Algorithm for Identifying Vestibular Neuronitis in Acute Dizziness: An Overview of Epidemiology, Pathogenesis, and Evidence-Based Guidelines for Diagnostic Approaches.开发用于识别急性头晕中前庭神经炎的诊断算法:流行病学、发病机制概述及基于证据的诊断方法指南
Cureus. 2025 Jan 28;17(1):e78126. doi: 10.7759/cureus.78126. eCollection 2025 Jan.
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Management of Sudden Sensorineural Hearing Loss in Multiple Sclerosis: A Comprehensive Case Report of a Patient with Bilateral Loss and Literature Review.
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Life (Basel). 2024 Jan 3;14(1):83. doi: 10.3390/life14010083.
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Positive horizontal-canal head impulse test is not a benign sign for acute vestibular syndrome with hearing loss.对于伴有听力损失的急性前庭综合征,水平半规管头脉冲试验阳性并非良性体征。
Front Neurol. 2022 Sep 26;13:941909. doi: 10.3389/fneur.2022.941909. eCollection 2022.
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