Ducheyne P, Healy K E
Department of Bioengineering, University of Pennsylvania, Philadelphia 19104.
J Biomed Mater Res. 1988 Dec;22(12):1137-63. doi: 10.1002/jbm.820221207.
Bone tissue ingrowth in porous materials is enhanced by the deposition of bioactive calcium phosphate ceramic linings onto the pore walls. These bioactive coatings can be deposited using several methods which yield a variety of coating efficiencies and thereby influence the mechanisms and kinetics of ion release from the metal. We analyzed the effect of plasma-spraying hydroxyapatite onto titanium and cobalt-chromium alloys by measuring the release of Ti, Al, V, Co, and Cr in vitro. Plasma-sprayed coatings significantly reduced the Ti and Al release from titanium-based alloy specimens. The tendencies of release from the cobalt-based specimens are less pronounced. The data substantiate that neither localized enhanced passive dissolution of metal ions nor ceramic shielding of the metal occurs. The Scanning Auger Electron Microprobe Spectroscopic data suggest that the dissipation of thermal and kinetic energy of the ceramic particle at the time of impact can produce compositional and structural changes in the metal surfaces. The resulting effects are significant for the titanium alloy but less significant for the Co-Cr alloy system.
通过在孔壁上沉积生物活性磷酸钙陶瓷衬里，可增强多孔材料中的骨组织向内生长。这些生物活性涂层可以通过多种方法沉积，这些方法会产生不同的涂层效率，从而影响金属离子释放的机制和动力学。我们通过测量钛、钴铬合金在体外Ti、Al、V、Co和Cr的释放，分析了等离子喷涂羟基磷灰石对其的影响。等离子喷涂涂层显著降低了钛基合金试样中Ti和Al的释放。钴基试样的释放趋势不太明显。数据证实，金属离子既没有局部增强的被动溶解，金属也没有被陶瓷屏蔽。扫描俄歇电子微探针光谱数据表明，陶瓷颗粒在撞击时的热能和动能耗散会使金属表面产生成分和结构变化。由此产生的影响对钛合金很显著，但对Co-Cr合金体系不太显著。
