Sirikham Thirawut, Tawanwongsri Weeratian, Rutnin Suthinee, Chanprapaph Kumutnart, Vachiramon Vasanop
Division of Dermatology, Department of Medicine, Suratthani Hospital, Suratthani, Thailand.
Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Case Rep Dermatol. 2020 Apr 14;12(1):76-81. doi: 10.1159/000507357. eCollection 2020 Jan-Apr.
We report a 23-year-old woman who presented with generalized scaly erythematous rash predominately on the upper trunk and hemorrhagic stomatitis. The histopathologic and immunopathologic findings were consistent with the diagnosis of paraneoplastic pemphigus. Castleman's tumor was diagnosed with computed tomography and exploratory laparotomy. A partial clinical improvement was observed after complete tumor removal and intravenous immunoglobulin administration. However, the patient died as a result of septicemia.
我们报告一名23岁女性,其表现为以躯干上部为主的全身性鳞屑性红斑皮疹和出血性口炎。组织病理学和免疫病理学检查结果符合副肿瘤性天疱疮的诊断。通过计算机断层扫描和剖腹探查诊断为Castleman病。在肿瘤完全切除并给予静脉注射免疫球蛋白后,观察到部分临床改善。然而,患者最终因败血症死亡。