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RPE epithelial-mesenchymal transition plays a critical role in the pathogenesis of proliferative vitreoretinopathy.

作者信息

Li Xiaohua, Zhao Mingwei, He Shikun

机构信息

Department of Ophthalmology, Henan Provincial People's Hospital, Zhengzhou 450003, China.

Henan Eye Hospital, Henan Eye Institute, Henan Key Laboratory of Ophthalmology and Visual Science, Zhengzhou 450003, China.

出版信息

Ann Transl Med. 2020 Mar;8(6):263. doi: 10.21037/atm.2020.03.86.

DOI:10.21037/atm.2020.03.86
PMID:32355707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7186684/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fca0/7186684/8b040d70ebcf/atm-08-06-263-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fca0/7186684/cc2c3aa348ad/atm-08-06-263-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fca0/7186684/8b040d70ebcf/atm-08-06-263-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fca0/7186684/cc2c3aa348ad/atm-08-06-263-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fca0/7186684/8b040d70ebcf/atm-08-06-263-f2.jpg

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miR-194 suppresses epithelial-mesenchymal transition of retinal pigment epithelial cells by directly targeting ZEB1.微小RNA-194通过直接靶向锌指E盒结合蛋白1抑制视网膜色素上皮细胞的上皮-间质转化。
Ann Transl Med. 2019 Dec;7(23):751. doi: 10.21037/atm.2019.11.90.
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CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer.CLDN6 通过 YAP1-snail1 轴促进胃癌的肿瘤进展。
Cell Death Dis. 2019 Dec 11;10(12):949. doi: 10.1038/s41419-019-2168-y.
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β-catenin activation down-regulates cell-cell junction-related genes and induces epithelial-to-mesenchymal transition in colorectal cancers.
Tacrolimus Modulates TGF-β Signaling-Related Genes and MicroRNAs in Human Retinal Pigment Epithelial Cells Activated by Lipopolysaccharide.
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Int J Mol Sci. 2025 Jun 4;26(11):5402. doi: 10.3390/ijms26115402.
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Effect of methotrexate/dexamethasone combination on epithelial-mesenchymal transition and inflammation gene expression of human RPE cells .甲氨蝶呤/地塞米松联合用药对人视网膜色素上皮细胞上皮-间质转化及炎症基因表达的影响
Front Pharmacol. 2025 Apr 30;16:1569703. doi: 10.3389/fphar.2025.1569703. eCollection 2025.
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