Villalobos Armelle Pérez-Cortés, Husain Shahid
Multi-Organ Transplant Unit, Division of Infectious Diseases, University Health Network, Toronto, ON, Canada.
Ann Transl Med. 2020 Mar;8(6):414. doi: 10.21037/atm.2020.03.102.
Lung transplantation has emerged as a lifesaving treatment for a wide range of advanced lung diseases. While the survival of lung transplant recipients continues to improve, infectious complications contribute substantially to morbidity and mortality following lung transplantation. The incidence of invasive fungal infections is variable, with a mean occurrence of 8.6%. The majority of fungal infections in lung transplant recipients are caused and species. This review provides an update in the current approaches for the diagnosis, management and prevention of fungal infections and the late complications that are associated.
肺移植已成为治疗多种晚期肺部疾病的一种挽救生命的疗法。虽然肺移植受者的生存率持续提高,但感染性并发症在很大程度上导致了肺移植后的发病率和死亡率。侵袭性真菌感染的发生率各不相同,平均发生率为8.6%。肺移植受者中的大多数真菌感染是由 和 菌种引起的。本综述提供了关于真菌感染的诊断、管理和预防以及相关晚期并发症的当前方法的最新情况。