Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, Canada.
HMU Health and Medical University Potsdam, Department of Neurosurgery, Ernst von Bergmann Hospital, Potsdam, Germany.
Neurosurgery. 2020 Jul 1;87(1):E23-E30. doi: 10.1093/neuros/nyaa112.
Both stereoelectroencephalography (SEEG) and subdural strip electrodes (SSE) are used for intracranial electroencephalographic recordings in the invasive investigation of patients with drug-resistant epilepsy.
To compare SEEG and SSE with respect to feasibility, complications, and outcome in this single-center study.
Patient characteristics, periprocedural parameters, complications, and outcome were acquired from a pro- and retrospectively managed databank to compare SEEG and SSE cases.
A total of 500 intracranial electroencephalographic monitoring cases in 450 patients were analyzed (145 SEEG and 355 SSE). Both groups were of similar age, gender distribution, and duration of epilepsy. Implantation of each SEEG electrode took 13.9 ± 7.6 min (20 ± 12 min for each SSE; P < .01). Radiation exposure to the patient was 4.3 ± 7.7 s to a dose area product of 14.6 ± 27.9 radcm2 for SEEG and 9.4 ± 8.9 s with 21 ± 22.4 radcm2 for SSE (P < .01). There was no difference in the length of stay (12.2 ± 7.2 and 12 ± 6.3 d). The complication rate was low in both groups. No infections were seen in SEEG cases (2.3% after SSE). The rate of hemorrhage was 2.8% for SEEG and 1.4% for SSE. Surgical outcome was similar.
SEEG allows targeting deeply situated foci with a non-inferior safety profile to SSE and seizure outcome comparable to SSE.
立体脑电图（SEEG）和硬膜下条电极（SSE）均用于颅内脑电图记录，以对耐药性癫痫患者进行侵袭性研究。
本单中心研究旨在比较 SEEG 和 SSE 在可行性、并发症和结果方面的差异。
从前瞻性和回顾性管理的数据库中获取患者特征、围手术期参数、并发症和结果，以比较 SEEG 和 SSE 病例。
共分析了 450 例患者的 500 例颅内脑电图监测病例（145 例 SEEG 和 355 例 SSE）。两组患者的年龄、性别分布和癫痫持续时间相似。每个 SEEG 电极的植入时间为 13.9±7.6 分钟（每个 SSE 为 20±12 分钟；P<.01）。患者的射线暴露量为 SEEG 为 4.3±7.7 秒，剂量面积产物为 14.6±27.9 radcm2，SSE 为 9.4±8.9 秒，剂量面积产物为 21±22.4 radcm2（P<.01）。住院时间无差异（SEEG 为 12.2±7.2 天，SSE 为 12±6.3 天）。两组并发症发生率均较低。SEEG 组无感染（SSE 组为 2.3%），SEEG 组出血发生率为 2.8%，SSE 组为 1.4%。手术结果相似。
SEEG 可靶向深部病灶，安全性不劣于 SSE，且与 SSE 的癫痫发作结果相当。
