Institute of Forensic Medicine, Medical Center - University of Freiburg, Forensic Molecular Biology, Albertstrasse 9, 79104, Freiburg, Germany.
Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Int J Legal Med. 2020 Sep;134(5):1563-1568. doi: 10.1007/s00414-020-02303-2. Epub 2020 May 1.
Mitochondrial DNA (mtDNA) control region sequences from hair samples of 213 individuals from Thailand were analyzed using Sanger sequencing. A total of 170 different haplotypes were identified, of which 146 occurred only once (unique haplotypes). The dataset showed a random match probability of 0.87% and a haplotype diversity of 0.9960. The samples were assigned to 85 different haplogroups with B5a, F1a1a, and M being the most frequent ones. Pairwise F-values between this and other Southeast and East Asian populations revealed significant but relatively low differences, indicating a close relation. Heteroplasmic positions were observed in 12.2% of hair samples confirming the frequent appearance of heteroplasmic positions in hairs. This dataset will complement existing data as an mtDNA reference for forensic investigations.
从泰国的 213 个人的头发样本中进行了线粒体 DNA(mtDNA)控制区序列的 Sanger 测序分析。总共鉴定出 170 种不同的单倍型,其中 146 种仅出现一次(独特单倍型)。该数据集显示随机匹配概率为 0.87%,单倍型多样性为 0.9960。这些样本被分配到 85 个不同的单倍群,其中 B5a、F1a1a 和 M 是最常见的。与其他东南亚和东亚人群的成对 F 值表明存在显著但相对较低的差异,表明存在密切关系。在 12.2%的头发样本中观察到异质位置,证实了异质位置在头发中频繁出现。该数据集将作为 mtDNA 法医调查参考数据的补充。