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[严重急性呼吸综合征冠状病毒2(SARS-CoV-2)大流行背景下精神药物面临的挑战]

[Challenges for psychotropics in the context of the SARS-Cov-2 pandemic].

作者信息

Javelot H, Llorca P-M, Meyer G, Fossati P, Haffen E

机构信息

Établissement Public de Santé Alsace Nord, Brumath, France; Laboratoire de Toxicologie et Pharmacologie Neuro Cardiovasculaire, Université de Strasbourg, Strasbourg, France.

CHU Clermont-Ferrand, EA 7280, Université Clermont Auvergne, France.

出版信息

Encephale. 2020 Jun;46(3S):S116-S118. doi: 10.1016/j.encep.2020.04.009. Epub 2020 Apr 23.

DOI:10.1016/j.encep.2020.04.009
PMID:32360037
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7177137/
Abstract

French recommendations have been proposed for psychotropics use and possible adaptations during the SARS-CoV-2 epidemic. Between uncertainties linked to the lack of data and speculations about possible benefits of psychotropics against the coronavirus, we propose here elements allowing to base the pharmacotherapeutic decisions potentially useful in Covid+ patients with psychiatric disorders.

摘要

法国已针对精神药物的使用以及在严重急性呼吸综合征冠状病毒2(SARS-CoV-2)疫情期间可能的调整提出了建议。在与数据缺乏相关的不确定性以及关于精神药物对冠状病毒可能益处的猜测之间,我们在此提出一些要素,以便为可能对患有精神疾病的新冠病毒阳性患者有用的药物治疗决策提供依据。

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本文引用的文献

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Immediate Impact of Coronavirus Disease 2019 on Electroconvulsive Therapy Practice.2019冠状病毒病对电休克治疗实践的即时影响。
J ECT. 2020 Jun;36(2):86-87. doi: 10.1097/YCT.0000000000000688.
2
[Informations on psychotropics and their adaptations for patients suffering from mental disorders in France during the SARS-CoV-2 epidemic].[关于法国在新冠疫情期间精神药物及其对精神障碍患者适应性的信息]
Encephale. 2020 Jun;46(3S):S14-S34. doi: 10.1016/j.encep.2020.04.006. Epub 2020 May 4.
3
[Ensuring mental health care during the SARS-CoV-2 epidemic in France: A narrative review].[法国新冠疫情期间的心理健康护理保障:一篇叙述性综述]
Encephale. 2020 Jun;46(3S):S3-S13. doi: 10.1016/j.encep.2020.03.001. Epub 2020 Apr 2.
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Consensus statement on the use of clozapine during the COVID-19 pandemic.关于在2019冠状病毒病大流行期间使用氯氮平的共识声明。
J Psychiatry Neurosci. 2020 May 1;45(3):222-223. doi: 10.1503/jpn.200061.
5
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2.基于网络的2019新型冠状病毒(2019-nCoV/SARS-CoV-2)药物重新利用研究
Cell Discov. 2020 Mar 16;6:14. doi: 10.1038/s41421-020-0153-3. eCollection 2020.
6
Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China.中国民众在 2019 年冠状病毒病(COVID-19)疫情初期的即时心理反应及相关因素。
Int J Environ Res Public Health. 2020 Mar 6;17(5):1729. doi: 10.3390/ijerph17051729.
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Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.新冠病毒的基因组特征和流行病学:对病毒起源和受体结合的影响。
Lancet. 2020 Feb 22;395(10224):565-574. doi: 10.1016/S0140-6736(20)30251-8. Epub 2020 Jan 30.
8
Pneumonia may be more frequent and have more fatal outcomes with clozapine than with other second-generation antipsychotics.与其他第二代抗精神病药物相比,使用氯氮平治疗时肺炎可能更常见,且致死率更高。
World Psychiatry. 2020 Feb;19(1):120-121. doi: 10.1002/wps.20707.
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Expert Rev Respir Med. 2019 Feb;13(2):173-180. doi: 10.1080/17476348.2019.1563486. Epub 2018 Dec 30.
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J Psychopharmacol. 2018 Nov;32(11):1167-1181. doi: 10.1177/0269881118795333. Epub 2018 Oct 18.