Institute of Ecology and Evolution, Biology Department, University of Oregon, Eugene, OR 97405, USA.
Institute of Ecology and Evolution, Biology Department, University of Oregon, Eugene, OR 97405, USA.
Trends Ecol Evol. 2020 Jul;35(7):573-582. doi: 10.1016/j.tree.2020.03.007. Epub 2020 Apr 29.
The importance of microbial associations to animals' development, physiology, and fitness is widely recognized. In most animals, these microbial associations must be developed anew with every generation, making microbiome assembly a critical ecological and evolutionary process. To fully understand neonate microbial colonization, we need to study the interacting effects of neonate, parents, nest, and external environment. We propose an integrative approach based on the concept of the 'nidobiome', a new unit of microbiome-host interactions, which brings together these key elements. We discuss the contribution of each element on microbial colonization at different stages of host development, and we provide a framework based on key developmental events to compare microbiome assembly across animal species.
微生物共生体对动物的发育、生理和适应能力至关重要，这一点已得到广泛认可。在大多数动物中，这些微生物共生体必须在每一代中重新建立，这使得微生物组的组装成为一个关键的生态和进化过程。为了全面了解新生儿的微生物定植，我们需要研究新生儿、父母、巢穴和外部环境之间的相互作用。我们基于“nidobiome”的概念提出了一种综合方法，这是一个新的微生物组-宿主相互作用单位，将这些关键要素结合在一起。我们讨论了在宿主发育的不同阶段每个要素对微生物定植的贡献，并提供了一个基于关键发育事件的框架，以便在不同动物物种之间比较微生物组的组装。
