尼日利亚癫痫患者的抑郁状况及其生活质量的相关因素。
Correlates of depression and quality of life among patients with epilepsy in Nigeria.
机构信息
Neuropsychiatric Hospital Aro, PMB 2002, Abeokuta, Ogun State, Nigeria; Boston University School of Public Health, Boston, MA, 02118, USA.
Neuropsychiatric Hospital Aro, PMB 2002, Abeokuta, Ogun State, Nigeria.
出版信息
Epilepsy Res. 2020 Aug;164:106344. doi: 10.1016/j.eplepsyres.2020.106344. Epub 2020 Apr 25.
OBJECTIVES
To determine the prevalence of Major Depressive Disorders (MDD) and its relationship to Quality of life.
DESIGN
A cross-sectional observational study.
SETTING
Out-Patient Clinic of the Neuropsychiatric Hospital, Abeokuta, Nigeria.
SUBJECTS
Patients with diagnosis of Epilepsy with Electroencephalogram (EEG) confirmation.
OUTCOME MEASURES
Depression and Quality of life.
RESULTS
The prevalence of current MDD was 11.9 %, and patients having at least 1 seizure per week were 5 times more likely to develop MDD (OR = 5.104, p = 0.014). The mean (SD) QOLIE-31 scores was 77.98 (13.32), with presence of MDD (β = -11.101, p = 0.0001); having at least 1 seizure/week (β = -6.653, p = 0.037) being independent predictors.
CONCLUSION
Depression is a common comorbidity in patients with epilepsy and is associated with a lower quality of life.
目的
确定重度抑郁障碍（MDD）的患病率及其与生活质量的关系。
设计
横断面观察性研究。
地点
尼日利亚阿贝库塔神经精神病医院门诊。
对象
经脑电图（EEG）证实诊断为癫痫的患者。
结局指标
抑郁和生活质量。
结果
当前 MDD 的患病率为 11.9%，每周至少发作 1 次的患者发生 MDD 的可能性是无发作患者的 5 倍（OR = 5.104，p = 0.014）。QOLIE-31 评分的平均值（SD）为 77.98（13.32），存在 MDD（β = -11.101，p = 0.0001）；每周至少发作 1 次（β = -6.653，p = 0.037）是独立的预测因素。
结论
抑郁是癫痫患者常见的共病，与生活质量较低有关。
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