Hochstadt Aviram, Havakuk Ofer, Chorin Ehud, Schwartz Arie Lorin, Merdler Ilan, Laufer Michal, Lubman Natan, Ghantous Eihab, Viskin Sami, Rosso Raphael
Department of Cardiology, Tel Aviv Sourasky Medical Center and Sackler School of Medicine, Tel Aviv University, Israel.
Department of Cardiology, Tel Aviv Sourasky Medical Center and Sackler School of Medicine, Tel Aviv University, Israel.
J Electrocardiol. 2020 May-Jun;60:138-141. doi: 10.1016/j.jelectrocard.2020.04.017. Epub 2020 Apr 26.
Wearable devices using photo-plethysmography (PPG) can accurately detect heart beats and may be useful for heart rate measurement and diagnosis of arrhythmias such as atrial fibrillation (AF). A previous study of a new portable PPG sensor (CardiacSense) showed high accuracy in heart rate measurement and AF detection in resting patients. We report a trial done to test the same device in active ambulatory patients with diverse characteristics.
A cohort of 24 ambulatory volunteers, underwent simultaneous PPG recording and continuous electrocardiogram (ECG) recording under different environmental conditions and situations. Per study protocol, the subjects were diverse in age, BMI, hair density and skin tone. Four subjects had AF. Heart rate measurement using the PPG device was compared to measurements by ECG.
Of 163,527 recorded ECG-detected beats in the trial, 86,929 (53.2%) were also recorded by the PPG device. Most undetected heart beats were due to motion induced noise. Correlation between ECG and PPG was high (R = 0.94, p < 0.0001), yet in subjects with AF correlation was lower (R = 0.80, p < 0.0001). A Bland-Altman analysis showed the mean difference between measurements was -0.7 ms (95% limit of agreement -93.8 to 92.2). A total of 86,217 (99.9%) of all RR measurements were reliably measured (RR difference within 100 ms). Reliability was sustained (>99.8%) in subjects of all groups including subjects with AF.
This study showed that, in the absence of movement-related noise, the CardiacSense PPG device can reliably detect HR in a variety of situations and subjects' characteristics.
使用光电容积脉搏波描记法（PPG）的可穿戴设备能够准确检测心跳，可能有助于心率测量以及心房颤动（AF）等心律失常的诊断。此前一项针对新型便携式PPG传感器（CardiacSense）的研究表明，该传感器在静息患者的心率测量和AF检测方面具有较高的准确性。我们报告了一项在具有不同特征的活动门诊患者中测试同一设备的试验。
24名门诊志愿者组成的队列在不同环境条件和情况下同时进行PPG记录和连续心电图（ECG）记录。根据研究方案，受试者在年龄、体重指数、头发密度和肤色方面存在差异。4名受试者患有AF。将使用PPG设备测量的心率与ECG测量结果进行比较。
在试验中记录的163,527次经ECG检测的心跳中，PPG设备也记录到了86,929次（53.2%）。大多数未检测到的心跳是由运动引起的噪声所致。ECG与PPG之间的相关性较高（R = 0.94，p < 0.0001），但在患有AF的受试者中相关性较低（R = 0.80，p < 0.0001）。Bland-Altman分析显示测量值之间的平均差异为-0.7毫秒（95%一致性界限为-93.8至92.2）。所有RR测量值中共有86,217次（99.9%）测量可靠（RR差异在100毫秒内）。在包括患有AF的受试者在内的所有组的受试者中，可靠性均得以维持（>99.8%）。
本研究表明，在不存在与运动相关噪声的情况下，CardiacSense PPG设备能够在各种情况和受试者特征下可靠地检测心率。
