Chorin Ehud, Hochstadt Aviram, Schwartz Arie Lorin, Matz Gil, Viskin Sami, Rosso Raphael
Department of Cardiology, Tel Aviv Sourasky Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
CardiacSense, Tel Aviv, Israel.
Front Cardiovasc Med. 2021 Jul 14;8:707621. doi: 10.3389/fcvm.2021.707621. eCollection 2021.
Assessing the effectiveness of novel bio-sensing technology (CardiacSense), for accuracy and reliability of automatic detection of life-threatening arrhythmias. This prospective study consisted of Eighteen patients (13 males and 5 females, mean age 59.4 ± 21.3 years) undergoing induction of ventricular tachycardia/fibrillation or provocation of transient ventricular asystole. We tested the detection of provoked ventricular arrhythmias by a wrist-worn watch-like device which uses photoplethysmography (PPG) technology to detect the cardiac rhythm. We used simultaneous electrocardiographic (ECG) recordings as gold standard for arrhythmia definition and confirmation of beat-to-beat detection. A total of 1,527 QRS complexes were recorded simultaneously by ECG and PPG. The overall correlation between the ECG (R-R intervals) and the PPG (G-G intervals) was high, with a correlation coefficient of R = 0.949 ( < 0.001). The device accurately detected all events of mimicked life endangering arrhythmias, including five events of transient (adenosine-induced) ventricular asystole as well as seven episodes of monomorphic ventricular tachycardia and 6 events of ventricular fibrillation. This proof-of-concept study suggests that wearable devices using PPG technology, currently used to detect atrial fibrillation, may also have a role as automatic detectors of life-threatening arrhythmias.
评估新型生物传感技术(CardiacSense)对危及生命的心律失常自动检测的准确性和可靠性。这项前瞻性研究包括18名患者(13名男性和5名女性,平均年龄59.4±21.3岁),他们正在接受室性心动过速/心室颤动的诱发或短暂性心室停搏的激发。我们通过一款类似手表的腕戴设备测试了对诱发的室性心律失常的检测,该设备使用光电容积脉搏波描记法(PPG)技术来检测心律。我们使用同步心电图(ECG)记录作为心律失常定义和逐搏检测确认的金标准。ECG和PPG同时记录了总共1527个QRS波群。ECG(R-R间期)和PPG(G-G间期)之间的总体相关性很高,相关系数R = 0.949(<0.001)。该设备准确检测到了所有模拟的危及生命的心律失常事件,包括5次短暂性(腺苷诱发)心室停搏事件、7次单形性室性心动过速发作和6次心室颤动事件。这项概念验证研究表明,目前用于检测心房颤动的采用PPG技术的可穿戴设备,也可能作为危及生命的心律失常的自动检测器发挥作用。