Farag Y, Nairn J G
Faculty of Pharmacy, University of Toronto, Ontario, Canada.
J Pharm Sci. 1988 Oct;77(10):872-5. doi: 10.1002/jps.2600771012.
Organic anions with similar properties, but different molecular weights, were bound to anion-exchange resins with different cross-linking. It was found that the capacity of the ion-exchange resin for the anions, the percentage of organic anion released, and the rate of release depends on the crosslinking of the ion-exchange resin, the molecular weight of the anion, and the moisture content of the resin. Self-diffusion coefficients for the release rates were determined.
具有相似性质但分子量不同的有机阴离子与具有不同交联度的阴离子交换树脂结合。结果发现,离子交换树脂对阴离子的容量、有机阴离子释放的百分比以及释放速率取决于离子交换树脂的交联度、阴离子的分子量和树脂的含水量。测定了释放速率的自扩散系数。