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2020 年印度针对 2019 年冠状病毒病的严重急性呼吸道疾病监测。

Severe acute respiratory illness surveillance for coronavirus disease 2019, India, 2020.

机构信息

Division of Epidemiology & Communicable Diseases, Indian Council of Medical Research, New Delhi, India.

ICMR-National Institute of Epidemiology, Chennai, Tamil Nadu, India.

出版信息

Indian J Med Res. 2020;151(2 & 3):236-240. doi: 10.4103/ijmr.IJMR_1035_20.

Abstract

BACKGROUND & OBJECTIVES: Sentinel surveillance among severe acute respiratory illness (SARI) patients can help identify the spread and extent of transmission of coronavirus disease 2019 (COVID-19). SARI surveillance was initiated in the early phase of the COVID-19 outbreak in India. We describe here the positivity for COVID-19 among SARI patients and their characteristics.

METHODS

SARI patients admitted at 41 sentinel sites from February 15, 2020 onwards were tested for COVID-19 by real-time reverse transcription-polymerase chain reaction, targeting E and RdRp genes of SARS-CoV-2. Data were extracted from Virus Research and Diagnostic Laboratory Network for analysis.

RESULTS

A total of 104 (1.8%) of the 5,911 SARI patients tested were positive for COVID-19. These cases were reported from 52 districts in 20 States/Union Territories. The COVID-19 positivity was higher among males and patients aged above 50 years. In all, 40 (39.2%) COVID-19 cases did not report any history of contact with a known case or international travel.

INTERPRETATION & CONCLUSIONS: COVID-19 containment activities need to be targeted in districts reporting COVID-19 cases among SARI patients. Intensifying sentinel surveillance for COVID-19 among SARI patients may be an efficient tool to effectively use resources towards containment and mitigation efforts.

摘要

背景与目的

严重急性呼吸道疾病(SARI)患者的哨点监测有助于确定 2019 冠状病毒病(COVID-19)的传播和范围。SARI 监测在印度 COVID-19 疫情的早期阶段启动。我们在此描述 SARI 患者中 COVID-19 的阳性率及其特征。

方法

自 2020 年 2 月 15 日起,对来自 41 个哨点的 SARI 患者进行 COVID-19 实时逆转录-聚合酶链反应检测,以检测 SARS-CoV-2 的 E 和 RdRp 基因。从病毒研究和诊断实验室网络提取数据进行分析。

结果

在接受检测的 5911 例 SARI 患者中,共有 104 例(1.8%)COVID-19 检测呈阳性。这些病例来自 20 个邦/联邦属地的 52 个区。COVID-19 阳性率在男性和 50 岁以上患者中较高。在所有 COVID-19 病例中,有 40 例(39.2%)没有报告与已知病例或国际旅行的任何接触史。

解释与结论

需要针对报告 SARI 患者中 COVID-19 病例的地区开展 COVID-19 遏制活动。加强对 SARI 患者 COVID-19 的哨点监测可能是一种有效利用资源进行遏制和缓解工作的有效工具。

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