Aljuboori Zaid, Burke William, Meyer Kimberly, Williams Brian
Department of Neurosurgery, University of Louisville, 220 Abraham Flexner Way, Suite 1500, Louisville, Kentucky, United States.
Surg Neurol Int. 2020 Apr 18;11:72. doi: 10.25259/SNI_15_2020. eCollection 2020.
Cancer pain can be debilitating and 10-20% of patients will have refractory pain despite optimal medical management. Here, we present a cost comparison of treating terminal cancer patients with intravenous (IV) narcotics, anterolateral cordotomy, or intrathecal pain pump (ITPP) placement.
We evaluated and treated 2 patients with metastatic breast cancer and expected survivals of <1 year. The first patient, a 53-year-old female, had tumor invasion of the right chest wall and had failed oral pain regimens; she was admitted to receive IV Dilaudid as patient-controlled analgesia (PCA). After 7 days of treatment without improvement, she underwent a left-sided C1-2 cordotomy. For her, the cost of the cordotomy was $18,462 and the expenses for 7 days hospital stay with PCA was $89,884; the total was $108,346. The second patient, a 60-year-old female, had severe somatic pain due to invasion by tumor of the left knee cap. She, too, has failed oral therapy and was receiving in-hospital IV Dilaudid PCA. Following 2 days of failed treatment, a morphine ITPP was placed and effectively treated her pain. In patient 2, the cost of the ITPP was $80,603 and the expenses for 8 days of the hospital stay with PCA came to $84,785; the total was $165,389.
The treatment of refractory pain in cancer patients is challenging. It requires invasive procedures such as cordotomy or ITPP. Although procedures may yield comparable pain control, there was a significant cost savings for cordotomy versus ITPP ($57,043 saved).
癌症疼痛可能使人虚弱,尽管进行了最佳的药物治疗,但仍有10%-20%的患者会出现顽固性疼痛。在此,我们对静脉注射(IV)麻醉剂、前外侧脊髓切开术或鞘内镇痛泵(ITPP)植入治疗晚期癌症患者的成本进行了比较。
我们评估并治疗了2例转移性乳腺癌患者,预计生存期<1年。首例患者为一名53岁女性,肿瘤侵犯右胸壁,口服止痛方案无效;她入院接受静脉注射度冷丁自控镇痛(PCA)。治疗7天后无改善,她接受了左侧C1-2脊髓切开术。对她来说,脊髓切开术的费用为18,462美元,PCA住院7天的费用为89,884美元;总计108,346美元。第二例患者为一名60岁女性,因左膝盖骨肿瘤侵犯而有严重的躯体疼痛。她口服治疗也无效,正在住院接受静脉注射度冷丁PCA。治疗2天无效后,植入了吗啡ITPP并有效缓解了她的疼痛。在患者2中,ITPP的费用为80,603美元,PCA住院8天的费用为84,785美元;总计165,389美元。
癌症患者顽固性疼痛的治疗具有挑战性。它需要诸如脊髓切开术或ITPP等侵入性手术。尽管这些手术可能产生相当的疼痛控制效果,但与ITPP相比,脊髓切开术节省了大量成本(节省57,043美元)。