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脊髓前侧柱切断术及鞘内镇痛泵置入术治疗难治性癌痛的成本分析

Cost analysis of cordotomy and intrathecal pain pump placement for refractory cancer pain.

作者信息

Aljuboori Zaid, Burke William, Meyer Kimberly, Williams Brian

机构信息

Department of Neurosurgery, University of Louisville, 220 Abraham Flexner Way, Suite 1500, Louisville, Kentucky, United States.

出版信息

Surg Neurol Int. 2020 Apr 18;11:72. doi: 10.25259/SNI_15_2020. eCollection 2020.

DOI:10.25259/SNI_15_2020
PMID:32363067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7193211/
Abstract

BACKGROUND

Cancer pain can be debilitating and 10-20% of patients will have refractory pain despite optimal medical management. Here, we present a cost comparison of treating terminal cancer patients with intravenous (IV) narcotics, anterolateral cordotomy, or intrathecal pain pump (ITPP) placement.

CASE DESCRIPTION

We evaluated and treated 2 patients with metastatic breast cancer and expected survivals of <1 year. The first patient, a 53-year-old female, had tumor invasion of the right chest wall and had failed oral pain regimens; she was admitted to receive IV Dilaudid as patient-controlled analgesia (PCA). After 7 days of treatment without improvement, she underwent a left-sided C1-2 cordotomy. For her, the cost of the cordotomy was $18,462 and the expenses for 7 days hospital stay with PCA was $89,884; the total was $108,346. The second patient, a 60-year-old female, had severe somatic pain due to invasion by tumor of the left knee cap. She, too, has failed oral therapy and was receiving in-hospital IV Dilaudid PCA. Following 2 days of failed treatment, a morphine ITPP was placed and effectively treated her pain. In patient 2, the cost of the ITPP was $80,603 and the expenses for 8 days of the hospital stay with PCA came to $84,785; the total was $165,389.

CONCLUSION

The treatment of refractory pain in cancer patients is challenging. It requires invasive procedures such as cordotomy or ITPP. Although procedures may yield comparable pain control, there was a significant cost savings for cordotomy versus ITPP ($57,043 saved).

摘要

背景

癌症疼痛可能使人虚弱,尽管进行了最佳的药物治疗,但仍有10%-20%的患者会出现顽固性疼痛。在此,我们对静脉注射(IV)麻醉剂、前外侧脊髓切开术或鞘内镇痛泵(ITPP)植入治疗晚期癌症患者的成本进行了比较。

病例描述

我们评估并治疗了2例转移性乳腺癌患者,预计生存期<1年。首例患者为一名53岁女性,肿瘤侵犯右胸壁,口服止痛方案无效;她入院接受静脉注射度冷丁自控镇痛(PCA)。治疗7天后无改善,她接受了左侧C1-2脊髓切开术。对她来说,脊髓切开术的费用为18,462美元,PCA住院7天的费用为89,884美元;总计108,346美元。第二例患者为一名60岁女性,因左膝盖骨肿瘤侵犯而有严重的躯体疼痛。她口服治疗也无效,正在住院接受静脉注射度冷丁PCA。治疗2天无效后,植入了吗啡ITPP并有效缓解了她的疼痛。在患者2中,ITPP的费用为80,603美元,PCA住院8天的费用为84,785美元;总计165,389美元。

结论

癌症患者顽固性疼痛的治疗具有挑战性。它需要诸如脊髓切开术或ITPP等侵入性手术。尽管这些手术可能产生相当的疼痛控制效果,但与ITPP相比,脊髓切开术节省了大量成本(节省57,043美元)。