Department of Respiratory, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Department of Radiology, Fuyang Hospital of Anhui Medical University, China, Anhui.
APMIS. 2020 Jun;128(6):423-432. doi: 10.1111/apm.13047.
Coronaviruses are a class of RNA viruses that can cause respiratory and intestinal infections in animals and humans. SARS-CoV, MERS-CoV, and a novel coronavirus (SARS-CoV-2 [2019-nCoV]) belong to the family Coronaviridae and the genus Betacoronavirus. At present, the understanding of SARS-CoV-2 is getting deeper and deeper. In order to better prevent and treat SARS-CoV-2, this article compares the infectivity, pathogenicity, and related clinical characteristics of the three human pathogenic coronaviruses, SARS-CoV-2, SARS-CoV, and MERS-CoV to help us further understand the pathogenic characteristics of novel coronaviruses.
冠状病毒是一类能够在动物和人类中引起呼吸道和肠道感染的 RNA 病毒。SARS-CoV、MERS-CoV 和一种新型冠状病毒(SARS-CoV-2[2019-nCoV])属于冠状病毒科和β冠状病毒属。目前,对 SARS-CoV-2 的了解越来越深入。为了更好地预防和治疗 SARS-CoV-2,本文比较了三种人类致病冠状病毒,即 SARS-CoV-2、SARS-CoV 和 MERS-CoV 的传染性、致病性和相关临床特征,以帮助我们进一步了解新型冠状病毒的致病特征。