Department of Biomedical Engineering, BK21+ Research Institute of Biomedical Engineering, School of ICT Convergence Engineering, College of Science and Technology, Konkuk University, Chungju, Korea.
Imaging Media Research Center, Korea Institute of Science and Technology, Seoul, Korea.
Technol Health Care. 2020;28(S1):335-345. doi: 10.3233/THC-209034.
A system that comprehensively analyzes a complex perceptual-motor behavior such as driving, by measuring changes in the central and autonomic nervous systems integrated with measurement of changes in vehicle operation, is lacking.
We aimed to develop a functional magnetic resonance imaging (fMRI)-compatible driving simulator to enable simultaneous measurement of physiological, kinematic, and brain activations.
The system mainly comprises a driving simulator and physiological/kinematic measurement. The driving simulator comprises a steering wheel, an accelerator, a brake pedal, and a virtual-reality optical system. The physiological system comprises a skin-conductance-level and a photoplethysmographic meter. The kinematic system comprises a 3-axis accelerometer and a 2-axis gyroscope attached to the accelerator foot. To evaluate the influence of the MR system on the MMSD, physiological and kinematic signals were measured.
The system did not blur or deform the MR image. Moreover, the main magnetic field, the gradient magnetic field, and the RF pulse of the MR system did not introduce noise into the physiological or kinematic signals.
This system can enable a comprehensive evaluation of cognitively complex behaviors such as driving, by quantitatively measuring and analyzing concurrent brain activity, autonomic nervous system activity, and human movement during simulated driving.
缺乏一种能够通过测量与车辆操作变化相结合的中枢和自主神经系统变化，全面分析驾驶等复杂感知运动行为的系统。
我们旨在开发一种功能磁共振成像（fMRI）兼容的驾驶模拟器，以实现生理、运动和大脑激活的同时测量。
该系统主要包括驾驶模拟器和生理/运动测量。驾驶模拟器包括方向盘、油门、刹车踏板和虚拟现实光学系统。生理系统包括皮肤电导水平和光体积描记仪。运动系统包括附着在油门上的 3 轴加速度计和 2 轴陀螺仪。为了评估 MR 系统对 MMSD 的影响，测量了生理和运动信号。
该系统没有使 MR 图像模糊或变形。此外，MR 系统的主磁场、梯度磁场和射频脉冲没有向生理或运动信号引入噪声。
该系统可以通过定量测量和分析模拟驾驶过程中的大脑活动、自主神经系统活动和人体运动，对驾驶等认知复杂行为进行全面评估。
