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本文引用的文献

1
Blockade of Pan-Fibroblast Growth Factor Receptors Mediates Bidirectional Effects in Lung Fibrosis.阻断多成纤维细胞生长因子受体可介导肺纤维化的双向作用。
Am J Respir Cell Mol Biol. 2020 Sep;63(3):317-326. doi: 10.1165/rcmb.2019-0090OC.
2
FGFR2 Is Required for AEC2 Homeostasis and Survival after Bleomycin-induced Lung Injury.成纤维细胞生长因子受体 2(FGFR2)在博来霉素诱导的肺损伤后对 AEC2 的稳态和存活是必需的。
Am J Respir Cell Mol Biol. 2020 May;62(5):608-621. doi: 10.1165/rcmb.2019-0079OC.
3
FGF10-FGFR2B Signaling Generates Basal Cells and Drives Alveolar Epithelial Regeneration by Bronchial Epithelial Stem Cells after Lung Injury.FGF10-FGFR2B 信号通过支气管上皮干细胞产生基底细胞,并在肺损伤后驱动肺泡上皮再生。
Stem Cell Reports. 2019 May 14;12(5):1041-1055. doi: 10.1016/j.stemcr.2019.04.003. Epub 2019 May 2.
4
Fibroblast growth factor 2 decreases bleomycin-induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation.成纤维细胞生长因子 2 可减少博来霉素诱导的肺纤维化,并抑制成纤维细胞胶原产生和肌成纤维细胞分化。
J Pathol. 2018 Sep;246(1):54-66. doi: 10.1002/path.5106. Epub 2018 Jul 5.
5
Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling.肺纤维化需要细胞自主的间充质成纤维细胞生长因子(FGF)信号传导。
J Biol Chem. 2017 Jun 23;292(25):10364-10378. doi: 10.1074/jbc.M117.791764. Epub 2017 May 9.
6
Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia.在支气管肺发育不良的小鼠模型中,成纤维细胞生长因子10(Fgf10)缺乏是致死的原因。
J Pathol. 2017 Jan;241(1):91-103. doi: 10.1002/path.4834. Epub 2016 Nov 26.
7
Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis.成纤维细胞生长因子-1减轻转化生长因子-β1诱导的肺纤维化。
J Pathol. 2016 Oct;240(2):197-210. doi: 10.1002/path.4768.
8
Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair.流感病毒感染远端肺上皮干细胞/祖细胞:对Fgfr2b驱动的上皮修复的影响。
PLoS Pathog. 2016 Jun 20;12(6):e1005544. doi: 10.1371/journal.ppat.1005544. eCollection 2016 Jun.
9
FGF9 and FGF18 in idiopathic pulmonary fibrosis promote survival and migration and inhibit myofibroblast differentiation of human lung fibroblasts in vitro.特发性肺纤维化中的FGF9和FGF18可促进人肺成纤维细胞的存活与迁移,并在体外抑制其向肌成纤维细胞的分化。
Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1;310(7):L615-29. doi: 10.1152/ajplung.00185.2015. Epub 2016 Jan 15.
10
Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis.特发性肺纤维化中FGF1-FGFRc表达增加。
Respir Res. 2015 Jul 3;16(1):83. doi: 10.1186/s12931-015-0242-2.

Fibroblast Growth Factor Inhibitors in Lung Fibrosis: Friends or Foes?

作者信息

Guzy Robert

机构信息

Department of Medicine, Section of Pulmonary and Critical Care Medicine The University of Chicago Chicago, Illinois.

出版信息

Am J Respir Cell Mol Biol. 2020 Sep;63(3):273-274. doi: 10.1165/rcmb.2020-0156ED.

DOI:10.1165/rcmb.2020-0156ED
PMID:32369705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7462340/
Abstract
摘要