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肝硬化患者胰腺手术的特殊性有哪些?

What are the Particularities of Pancreatic Surgery in the Cirrhotic Patient?

作者信息

Schwarz Lilian, Regimbeau Jean-Marc, Rebibo Lionel

出版信息

Chirurgia (Bucur). 2020 Mar-Apr;115(2):185-190. doi: 10.21614/chirurgia.115.2.185.

Abstract

The objective of this work was to review the entire literature on pancreatic surgery in order to best define the surgical indications and the specifics of their management. The bibliographic research was done on Pubmed over the period from January 1995 to June 2015, using French and English as the languages of publication. The two main indications discussed here are the management of cancer and chronic pancreatitis. Surgery in the cirrhotic patient exposes the patient to a higher risk of complications than in the non-cirrhotic patient. Child-Pugh and MELD scores should be used to assess risk and guide operative decision. Child-Pugh classes B and a MELD score value greater than 15 are associated with higher morbidity and mortality. However, if suitable selection is made of cirrhotic patients who are candidates for pancreatic surgery, long-term survival seems to be equivalent to the non-cirrhotic group. No risk factors for long-term survival have been reported. In conclusion, cirrhotic patients, candidates for pancreatic surgery must be correctly selected, cirrhosis exposes to a higher risk of postoperative morbidity and mortality.

摘要

这项工作的目的是回顾有关胰腺手术的全部文献,以便更好地界定手术适应症及其管理细节。文献研究于1995年1月至2015年6月期间在PubMed上进行,以法语和英语作为发表语言。这里讨论的两个主要适应症是癌症的管理和慢性胰腺炎。肝硬化患者接受手术比非肝硬化患者面临更高的并发症风险。应使用Child-Pugh和MELD评分来评估风险并指导手术决策。Child-Pugh B级和MELD评分大于15与更高的发病率和死亡率相关。然而,如果对适合进行胰腺手术的肝硬化患者进行适当选择,长期生存率似乎与非肝硬化组相当。尚未报道长期生存的危险因素。总之,必须正确选择适合进行胰腺手术的肝硬化患者,肝硬化会增加术后发病和死亡的风险。

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