Gingras Alexandre R, Ginsberg Mark H
Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0726, USA.
Curr Biol. 2020 May 4;30(9):R397-R400. doi: 10.1016/j.cub.2020.02.068.
New work describes a novel mechanism of mechanotransduction, whereby force-induced membrane deformation activates integrins by disrupting the association of the transmembrane domains of α and β integrins.
新的研究描述了一种新型的机械转导机制，即力诱导的膜变形通过破坏α和β整合素跨膜结构域之间的结合来激活整合素。
