Kolling Institute of Medical Research, Institute of Bone and Joint Research, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Department of Rheumatology, Royal North Shore Hospital , Sydney, Australia.
Health Qual Life Outcomes. 2020 May 5;18(1):121. doi: 10.1186/s12955-020-01364-6.
The Patient Activation Measure (PAM-13) was developed using Rasch analysis to assess knowledge, skills and confidence in the management of one's health. Previous studies report positive relationships between PAM-13 scores, self-management behaviours and longitudinal health outcomes in adults with chronic disease. There is little extant measurement property evidence for the use of PAM-13 in specific osteoarthritis (OA) populations. This study tested measurement properties of the PAM-13 in people living with hip and knee OA.
Item response frequency analysis was conducted. Rasch analysis evaluated the fit of the PAM-13 data to the Rasch model. Model-data fit was evaluated using infit and outfit statistics; person/item reliability and person separation indices were computed. Unidimensionality was evaluated using Principal Components Analysis of Rasch residuals and the data were assessed for item redundancy. Differential Item Functioning (DIF) examined bias in respondent subgroups and correlations tested relationships between PAM-13 and other patient-reported outcomes.
Two-hundred-and-seventeen PAM-13 surveys were completed; there were no missing responses, floor or ceiling effects. Person and item reliability were acceptable (0.98 and 0.87 respectively) with good separation (person separation index 2.58). Unidimensionality was evaluated, with 49.4% of the variance explained by the first eigenvector. There was evidence of potential local response-dependence. The Rasch fit statistics were acceptable (except for item-2). There were some issues identified with targeting of the PAM-13 items to people with higher ability and the item difficulty order was different to that proposed in original cohorts. Significant DIF was identified for sex and educational level for a small number of items. PAM-13 scores were moderately correlated with depressive symptoms on the Depression Anxiety Stress Scale and Assessment of Quality of Life-6D. There were small correlations between PAM-13 and Knee injury and Osteoarthritis Outcome Score pain and activities of daily living scores.
This study provides some evidence of adequate person and item reliability, unidimensionality, and construct validity to support the use of PAM-13 to measure patient activation in people living with hip and knee OA. Possible limitations regarding targeting, different item difficulty order, DIF and local response dependence should be investigated in future research.
患者激活量表(PAM-13)是使用 Rasch 分析开发的,用于评估患者管理自身健康的知识、技能和信心。先前的研究报告称,在患有慢性疾病的成年人中,PAM-13 评分与自我管理行为和纵向健康结果之间存在积极关系。在特定的骨关节炎(OA)人群中,关于 PAM-13 使用的测量特性证据很少。本研究测试了 PAM-13 在患有髋部和膝关节 OA 的人群中的测量特性。
进行了项目反应频率分析。Rasch 分析评估了 PAM-13 数据与 Rasch 模型的拟合程度。使用 infit 和 outfit 统计数据评估模型数据拟合度;计算了人员/项目可靠性和人员分离指数。使用 Rasch 残差的主成分分析评估了单维性,并评估了项目冗余度。差异项目功能(DIF)检查了受访者亚组的偏差,相关性测试了 PAM-13 与其他患者报告的结果之间的关系。
完成了 217 份 PAM-13 调查,没有缺失响应、地板或天花板效应。人员和项目可靠性是可以接受的(分别为 0.98 和 0.87),且具有良好的分离度(人员分离指数为 2.58)。评估了单维性,第一个特征向量解释了 49.4%的方差。有证据表明存在潜在的局部响应依赖性。Rasch 拟合统计数据是可以接受的(除了项目 2)。在针对能力较高的人群时,PAM-13 项目的目标定位存在一些问题,项目难度顺序与原始队列提出的顺序不同。对于少数项目,发现了性别和教育水平的显著 DIF。PAM-13 评分与抑郁症状在抑郁焦虑应激量表和生活质量评估 6D 上中度相关。PAM-13 与膝关节损伤和骨关节炎结局评分疼痛和日常生活活动评分之间存在较小的相关性。
本研究提供了一些关于人员和项目可靠性、单维性和结构有效性的充分证据,支持在患有髋部和膝关节 OA 的人群中使用 PAM-13 来衡量患者的激活程度。在未来的研究中,应调查针对目标人群、项目难度顺序、DIF 和局部响应依赖性等方面的可能限制。