Güney Erengül, Alnıak İzgi, Erkıran Murat
Bakırköy Prof. Mazhar Osman Training and Research Hospital for Psychiatry and Neurology, Bakırköy, İstanbul, 34280, Turkey.
Bakırköy Prof. Mazhar Osman Training and Research Hospital for Psychiatry and Neurology, Bakırköy, İstanbul, 34280, Turkey.
Asian J Psychiatr. 2020 Aug;52:102068. doi: 10.1016/j.ajp.2020.102068. Epub 2020 Apr 21.
Non-suicidal self-injury (NSSI) has been shown as a characteristic feature in many clinical populations in recent years and schizophrenia is one of the most common psychiatric disorders which is associated with NSSI. In this study, we aimed to investigate predictors of NSSI in patients with schizophrenia spectrum disorders (SSD) and the role of lifetime substance use disorder (SUD). A sample of 165 patients with a diagnosis of SSD who were in remission participated in the study. Lifetime NSSI was assessed using the Inventory of Statements About Self-injury (ISAS). Lifetime SUD were evaluated. Logistic regression analysis was conducted to predict NSSI. SUD was found to be related to NSSI in patients with SSD, and it was associated with an approximately fourfold increase in the risk of NSSI. The rates of lifetime SUD in our sample and in the NSSI (+) group were 38.2 % and 55.6 %, respectively. The most commonly abused substances among patients with NSSI were cannabis and synthetic cannabinoids. The prevalence of NSSI was 43.6 % in our sample. 'Self-cutting' was the most common type and 'affect regulation' was the most common function of NSSI. One of the most significant risk factors for NSSI was a previous history of suicide attempts. SUD appears to be a significant predictor of NSSI in patients with SSD. Further investigation of treatable risk factors such as SUD which are related to NSSI is needed. It is also essential to screen SSD patients for NSSI due to the probable relation to high risk of suicide.
近年来，非自杀性自伤（NSSI）已成为许多临床人群的一个特征，精神分裂症是与NSSI相关的最常见精神疾病之一。在本研究中，我们旨在调查精神分裂症谱系障碍（SSD）患者中NSSI的预测因素以及终生物质使用障碍（SUD）的作用。165名处于缓解期的SSD诊断患者参与了该研究。使用自伤陈述量表（ISAS）评估终生NSSI情况。评估终生SUD情况。进行逻辑回归分析以预测NSSI。发现SUD与SSD患者的NSSI相关，且与NSSI风险增加约四倍有关。我们样本和NSSI（+）组中的终生SUD发生率分别为38.2%和55.6%。NSSI患者中最常滥用的物质是大麻和合成大麻素。我们样本中NSSI的患病率为43.6%。“自我切割”是最常见的类型，“情绪调节”是NSSI最常见的功能。NSSI最重要的危险因素之一是既往自杀未遂史。SUD似乎是SSD患者NSSI的一个重要预测因素。需要进一步调查与NSSI相关的可治疗危险因素，如SUD。由于可能与高自杀风险相关，对SSD患者进行NSSI筛查也至关重要。
