Grabein Béatrice, Ebenhoch Michael, Kühnen Ernst, Thalhammer Florian
Stabsstelle Klinische Mikrobiologie und Krankenhaushygiene, Klinikum der Universität München, Munich, Germany.
Stabsstelle Hygiene, Klinische Infektiologie und Mikrobiologie, BG-Unfallklinik Murnau, Germany.
GMS Infect Dis. 2020 Mar 26;8:Doc04. doi: 10.3205/id000048. eCollection 2020.
This is the sixteenth chapter of the guideline "Calculated initial parenteral treatment of bacterial infections in adults - update 2018" in the 2 updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been translated to address an international audience. Infections due to multiresistant Gram-negative rods are challenging. In this chapter recommendations for targeted therapy for infections caused by ESBL-producing Enterobacteriaceae, carbapenemase-producing Enterobacteriaceae and carbapenem-resistant are given, based on the limited available evidence.
这是《成人细菌性感染的初始肠外计算治疗指南 - 2018年更新》第二版中的第十六章。保罗·埃利希化疗协会(PEG)的德国指南已被翻译,以面向国际读者。多重耐药革兰氏阴性杆菌引起的感染具有挑战性。本章基于有限的现有证据,给出了针对产超广谱β-内酰胺酶肠杆菌科细菌、产碳青霉烯酶肠杆菌科细菌和耐碳青霉烯类细菌所致感染的靶向治疗建议。