Wang Zhengdi, Hu Tingting, Liang Ruizheng, Wei Min
State Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, China.
Front Chem. 2020 Apr 17;8:320. doi: 10.3389/fchem.2020.00320. eCollection 2020.
Zero-dimensional (0D) nanomaterials, including graphene quantum dots (GQDs), carbon quantum dots (CQDs), fullerenes, inorganic quantum dots (QDs), magnetic nanoparticles (MNPs), noble metal nanoparticles, upconversion nanoparticles (UCNPs) and polymer dots (Pdots), have attracted extensive research interest in the field of biosensing in recent years. Benefiting from the ultra-small size, quantum confinement effect, excellent physical and chemical properties and good biocompatibility, 0D nanomaterials have shown great potential in ion detection, biomolecular recognition, disease diagnosis and pathogen detection. Here we first introduce the structures and properties of different 0D nanomaterials. On this basis, recent progress and application examples of 0D nanomaterials in the field of biosensing are discussed. In the last part, we summarize the research status of 0D nanomaterials in the field of biosensing and anticipate the development prospects and future challenges in this field.
零维（0D）纳米材料，包括石墨烯量子点（GQDs）、碳量子点（CQDs）、富勒烯、无机量子点（QDs）、磁性纳米颗粒（MNPs）、贵金属纳米颗粒、上转换纳米颗粒（UCNPs）和聚合物点（Pdots），近年来在生物传感领域引起了广泛的研究兴趣。得益于其超小尺寸、量子限域效应、优异的物理和化学性质以及良好的生物相容性，零维纳米材料在离子检测、生物分子识别、疾病诊断和病原体检测方面展现出了巨大潜力。在此，我们首先介绍不同零维纳米材料的结构和性质。在此基础上，讨论零维纳米材料在生物传感领域的最新进展和应用实例。在最后一部分，我们总结了零维纳米材料在生物传感领域的研究现状，并展望了该领域的发展前景和未来挑战。
