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本文引用的文献

1
Impact of the COVID-19 Pandemic on Parkinson's Disease and Movement Disorders.2019冠状病毒病大流行对帕金森病和运动障碍的影响。
Mov Disord Clin Pract. 2020 Apr 16;7(4):357-360. doi: 10.1002/mdc3.12953. eCollection 2020 May.
2
Neurological Complications of Coronavirus Disease (COVID-19): Encephalopathy.冠状病毒病(COVID-19)的神经系统并发症:脑病
Cureus. 2020 Mar 21;12(3):e7352. doi: 10.7759/cureus.7352.
3
Hematological findings and complications of COVID-19.COVID-19 的血液学表现及并发症。
Am J Hematol. 2020 Jul;95(7):834-847. doi: 10.1002/ajh.25829. Epub 2020 May 23.
4
A first case of meningitis/encephalitis associated with SARS-Coronavirus-2.首例与 SARS-CoV-2 相关的脑膜炎/脑炎。
Int J Infect Dis. 2020 May;94:55-58. doi: 10.1016/j.ijid.2020.03.062. Epub 2020 Apr 3.
5
The Impact of the COVID-19 Pandemic on Parkinson's Disease: Hidden Sorrows and Emerging Opportunities.新冠疫情对帕金森病的影响:隐藏的困境与新出现的机遇
J Parkinsons Dis. 2020;10(2):351-354. doi: 10.3233/JPD-202038.
6
The Invisible Hand - Medical Care during the Pandemic.无形之手——疫情期间的医疗护理
N Engl J Med. 2020 Apr 23;382(17):1586-1587. doi: 10.1056/NEJMp2006607. Epub 2020 Apr 2.
7
Telemedicine for Hyperkinetic Movement Disorders.远程医疗治疗运动障碍
Tremor Other Hyperkinet Mov (N Y). 2020 Feb 17;10. doi: 10.7916/tohm.v0.698. eCollection 2020.
8
The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients.SARS-CoV2 的神经侵袭性可能在 COVID-19 患者的呼吸衰竭中起作用。
J Med Virol. 2020 Jun;92(6):552-555. doi: 10.1002/jmv.25728. Epub 2020 Mar 11.
9
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.中国武汉地区 2019 年新型冠状病毒感染患者的临床特征。
Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
10
Acute lethargy after abrupt apomorphine withdrawal in Parkinson's disease.帕金森病患者突然停用阿扑吗啡后出现急性嗜睡。
J Neurol Sci. 2019 Sep 15;404:44-46. doi: 10.1016/j.jns.2019.07.011. Epub 2019 Jul 10.

人道主义危机时期帕金森病患者的先进疗法管理:COVID-19经验

Management of Advanced Therapies in Parkinson's Disease Patients in Times of Humanitarian Crisis: The COVID-19 Experience.

作者信息

Fasano Alfonso, Antonini Angelo, Katzenschlager Regina, Krack Paul, Odin Per, Evans Andrew H, Foltynie Thomas, Volkmann Jens, Merello Marcelo

机构信息

Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, University Health Network, Division of Neurology University of Toronto Toronto Ontario Canada.

Krembil Brain Institute Toronto Ontario Canada.

出版信息

Mov Disord Clin Pract. 2020 May 4;7(4):361-372. doi: 10.1002/mdc3.12965. eCollection 2020 May.

DOI:10.1002/mdc3.12965
PMID:32373652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7197306/
Abstract

BACKGROUND

Although the COVID-19 pandemic is affecting a relatively small proportion of the global population, its effects have already reached everyone. The pandemic has the potential to differentially disadvantage chronically ill patients, including those with Parkinson's disease (PD). The first health care reaction has been to limit access to clinics and neurology wards to preserve fragile patients with PD from being infected. In some regions, the shortage of medical staff has also forced movement disorders neurologists to provide care for patients with COVID-19.

OBJECTIVE

To share the experience of various movement disorder neurologists operating in different world regions and provide a common approach to patients with PD, with a focus on those already on advanced therapies, which may serve as guidance in the current pandemic and for emergency situations that we may face in the future.

CONCLUSION

Most of us were unprepared to deal with this condition given that in many health care systems, telemedicine has been only marginally available or only limited to email or telephone contacts. In addition, to ensure sufficient access to intensive care unit beds, most elective procedures (including deep brain stimulation or the initiation of infusion therapies) have been postponed. We all hope there will soon be a time when we will return to more regular hospital schedules. However, we should consider this crisis as an opportunity to change our approach and encourage our hospitals and health care systems to facilitate the remote management of chronic neurological patients, including those with advanced PD.

摘要

背景

尽管新冠疫情影响的全球人口比例相对较小,但其影响已波及每个人。这场疫情有可能对慢性病患者,包括帕金森病(PD)患者造成不同程度的不利影响。医疗保健的首要反应是限制进入诊所和神经科病房,以保护脆弱的PD患者不被感染。在一些地区,医护人员短缺也迫使运动障碍神经科医生为新冠患者提供治疗。

目的

分享世界各地不同运动障碍神经科医生的经验,并为PD患者提供一种通用的治疗方法,重点关注那些已经接受先进疗法的患者,这可能为当前疫情以及我们未来可能面临的紧急情况提供指导。

结论

鉴于在许多医疗保健系统中,远程医疗仅在边缘可用或仅限于电子邮件或电话联系,我们大多数人都没有准备好应对这种情况。此外,为确保有足够的重症监护病房床位,大多数择期手术(包括脑深部电刺激或开始输液治疗)都已推迟。我们都希望很快能回到更正常的医院日程安排。然而,我们应该将这场危机视为一个改变我们治疗方法的机会,并鼓励我们的医院和医疗保健系统促进对慢性神经疾病患者,包括晚期PD患者的远程管理。