Karnati Sreenivas, Kollikonda Swapna, Abu-Shaweesh Jalal
Department of Pediatrics, Cleveland Clinic Children's, Cleveland, OH, USA.
Department of Obstetrics and Gynecology, Women's Health Institute, Cleveland Clinic, Cleveland, OH, USA.
Int J Pediatr Adolesc Med. 2020 Mar;7(1):36-44. doi: 10.1016/j.ijpam.2020.02.006. Epub 2020 Feb 25.
Late preterm infants, defined as newborns born between 34-36 weeks of gestational age, constitute a unique group among all premature neonates. Often overlooked because of their size when compared to very premature infants, this population is still vulnerable because of physiological and structural immaturity. Comprising nearly 75% of babies born less than 37 weeks of gestation, late preterm infants are at increased risk for morbidities involving nearly every organ system as well as higher risk of mortality when compared to term neonates. Neurodevelopmental impairment has especially been a concern for these infants. Due to various reasons, the rate of late preterm births continue to rise worldwide. Caring for this high risk population contributes a significant financial burden to health systems. This article reviews recent trends in regarding rate of late preterm births, common morbidities and long term outcomes with special attention to neurodevelopmental outcomes.
晚期早产儿定义为孕周在34至36周之间出生的新生儿，在所有早产新生儿中构成一个独特的群体。与极早产儿相比，他们常因体型而被忽视，但由于生理和结构不成熟，这一群体仍然很脆弱。晚期早产儿占孕周小于37周出生婴儿的近75%，与足月儿相比，他们发生几乎累及每个器官系统疾病的风险增加，死亡风险也更高。神经发育障碍一直是这些婴儿特别令人担忧的问题。由于各种原因，全球晚期早产的发生率持续上升。照顾这一高危人群给卫生系统带来了巨大的经济负担。本文回顾了晚期早产发生率、常见疾病及长期结局的最新趋势，特别关注神经发育结局。
