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沟通干预随机对照试验对实现治疗目标讨论的效果。

Effects of a Communication Intervention Randomized Controlled Trial to Enable Goals-of-Care Discussions.

机构信息

Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY.

Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY.

出版信息

JCO Oncol Pract. 2020 Sep;16(9):e1015-e1028. doi: 10.1200/OP.20.00040. Epub 2020 May 6.

Abstract

PURPOSE

Patients with advanced cancer often have a poor understanding of cancer incurability, which correlates with more aggressive treatment near the end of life (EOL). We sought to determine whether training oncologists to elicit patient values for goals-of-care (GoC) discussions will increase and improve these discussions. We explored its impact on use of aggressive care at EOL.

METHODS

We enrolled and used block randomization to assign 92% of solid tumor oncologists to 2-hour communication skills training and four coaching sessions. We surveyed 265 patient with newly diagnosed advanced cancer with < 2-year life expectancy at baseline and 6 months. We assessed prevalence and quality of GoC communication, change in communication skills, and use of aggressive care in the last month of life.

RESULTS

Intervention (INT) oncologists' (n = 11) skill to elicit patient values increased (27%-55%), while usual care (UC) oncologists' (n = 11) skill did not (9%-0%; = .01). Forty-eight percent (n = 74) INT 51% (n = 56) UC patients reported a GoC discussion ( = .61). There was no difference in the prevalence or quality of GoC communication between groups (global odds ratio, 0.84; 95% CI, 0.57 to 1.23). Within 6 months, there was no difference in deaths (18 INT 16 UC; = .51), mean hospitalizations (0.47 INT 0.42 UC; = .63), intensive care unit admissions (5% INT 9% UC; = .65), or chemotherapy (26% INT 16% UC; = .39).

CONCLUSION

Use of a coaching model focused on teaching oncologists to elicit patient values improved that skill but did not increase prevalence or quality of GoC discussions among patients with advanced cancer. There was no impact on high care utilization at EOL.

摘要

目的

晚期癌症患者通常对癌症不可治愈的理解较差,这与生命末期(EOL)更积极的治疗相关。我们旨在确定培训肿瘤医生进行治疗目标讨论是否会增加和改善这些讨论,并探讨其对 EOL 时采用积极治疗的影响。

方法

我们纳入并采用区组随机分组将 92%的实体瘤肿瘤医生分配至 2 小时沟通技巧培训和 4 次辅导课程。我们在基线时招募了 265 名预期寿命<2 年的新发晚期癌症患者,并在 6 个月时进行了评估。我们评估了治疗目标沟通的普遍性和质量、沟通技巧的变化以及生命最后一个月的积极治疗使用情况。

结果

干预(INT)组肿瘤医生(n=11)引出患者价值观的能力提高(27%-55%),而常规护理(UC)组肿瘤医生(n=11)的能力没有提高(9%-0%;P=.01)。48%(n=74)INT 组和 51%(n=56)UC 组患者报告进行了治疗目标讨论(P=.61)。两组之间治疗目标沟通的普遍性或质量没有差异(总体优势比,0.84;95%CI,0.57 至 1.23)。在 6 个月内,INT 组和 UC 组的死亡人数(18 例 INT 和 16 例 UC;P=.51)、平均住院时间(0.47 INT 和 0.42 UC;P=.63)、重症监护病房入院率(5% INT 和 9% UC;P=.65)或化疗使用率(26% INT 和 16% UC;P=.39)均无差异。

结论

使用专注于教授肿瘤医生引出患者价值观的辅导模式提高了这一技能,但并未增加晚期癌症患者治疗目标讨论的普遍性或质量。这对 EOL 时的高医疗利用率没有影响。

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