Ma Xiaohua, Li Lan, Jin Tao, Xia Qing
Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2020 Feb 29;40(2):190-195. doi: 10.12122/j.issn.1673-4254.2020.02.09.
To evaluate the efficacy of harmless acute pancreatitis score (HAPS) on admission for predicting mild acute pancreatitis (MAP).
We prospectively collected the data from consecutive AP patients admitted to West China Hospital between January, 2016 and August, 2017, and HAPS scores were calculated on admission. The clinical outcomes of the patients with harmless AP (HAPS>2) and those with non-harmless AP (HAPS≤2) were compared. MAP was defined based on the severity classification of 2012 Revised Atlanta guidelines. The area under the curve (AUC) of the receiver- operator characteristic curve (ROC), specificity, sensitivity, positive predictive value (PPV) and negative predictive value (NPV) of HAPS on admission for predicting MAP were analyzed.
Of the 703 patients with AP analyzed, 182 were predicted to have harmless AP and 521 to have non- harmless AP, and the patients in the latter group had significantly worse clinical outcomes ( < 0.001). The total number of patients with MAP was 359 in the study. The specificity, the sensitivity, the PPV and NPV of HAPS on admission for predicting MAP was 97.7% (95% : 95.4-99.0), 48.2% (95% : 42.9-53.3), 95.6% (95% : 91.5- 98.1) and 64.1% (95% : 59.8- 68.2), respectively, and the AUC was 0.749 (95% : 0.72- 0.78).
HAPS score on admission can accurately predict MAP.
评估入院时无害性急性胰腺炎评分(HAPS)对预测轻度急性胰腺炎(MAP)的有效性。
前瞻性收集2016年1月至2017年8月期间连续入住华西医院的急性胰腺炎(AP)患者的数据,并在入院时计算HAPS评分。比较无害性AP(HAPS>2)和非无害性AP(HAPS≤2)患者的临床结局。根据2012年修订的亚特兰大指南的严重程度分类来定义MAP。分析入院时HAPS预测MAP的受试者工作特征曲线(ROC)的曲线下面积(AUC)、特异性、敏感性、阳性预测值(PPV)和阴性预测值(NPV)。
在分析的703例AP患者中,182例被预测为无害性AP,521例为非无害性AP,后一组患者的临床结局明显更差(<0.001)。本研究中MAP患者总数为359例。入院时HAPS预测MAP的特异性、敏感性、PPV和NPV分别为97.7%(95%:95.4 - 99.0)、48.2%(95%:42.9 - 53.3)、95.6%(95%:91.5 - 98.1)和64.1%(95%:59.8 - 68.2),AUC为0.749(95%:0.72 - 0.78)。
入院时的HAPS评分可准确预测MAP。