Mei Juhua, Zhang Qi, Gong Xue, Xu Jinmei, Pan Songbin, Pan Xiaofeng, Wang Junli, Liu Minzhen
Wuhan First Hospital, Wuhan 430022, China.
Hubei University of Chinese Medicine, Wuhan 430065, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2020 Jan 30;40(1):131-136. doi: 10.12122/j.issn.1673-4254.2020.01.21.
To study sleep quality and cognitive status and their correlation in patients with persistent postural and perceptual dizziness (PPPD).
We assessed sleep quality and cognitive function among 70 patients with PPPD and 70 age-matched heathy volunteers using Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Pittsburgh Sleep Quality Index and polysomnography (PSG).
The patients had a mean MMSE score of 25.10±3.87 and a mean MoCA score of 23.10±6.11, both suggesting mild cognitive impairment of the patients. The mean PSQI score of the patients was 14.60 ± 2.06, suggesting moderate insomnia among the patients. The MMSE scores in 3 dimensions (attention, memory and recall ability) and the dimension scores of MoCA for visual space and executive ability, attention and delayed recall all showed significant positive correlations with PSQI scores for sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disorders and daytime dysfunction.
Moderate sleep disorder and mild cognitive dysfunction are common in PPPD patients. Sleep quality is correlated with cognitive function among these patients, suggesting that improving sleep quality of the patients helps to improve their cognitive function.
研究持续性姿势性感知性头晕（PPPD）患者的睡眠质量和认知状态及其相关性。
我们使用简易精神状态检查表（MMSE）、蒙特利尔认知评估量表（MoCA）、匹兹堡睡眠质量指数和多导睡眠图（PSG），对70例PPPD患者和70例年龄匹配的健康志愿者的睡眠质量和认知功能进行了评估。
患者的平均MMSE评分为25.10±3.87，平均MoCA评分为23.10±6.11，均提示患者存在轻度认知障碍。患者的平均PSQI评分为14.60±2.06，提示患者存在中度失眠。MMSE评分的3个维度（注意力、记忆力和回忆能力）以及MoCA量表中视觉空间与执行能力、注意力和延迟回忆的维度评分，均与PSQI量表中睡眠质量、入睡潜伏期、睡眠时间、睡眠效率、睡眠障碍和日间功能障碍的评分呈显著正相关。
中度睡眠障碍和轻度认知功能障碍在PPPD患者中较为常见。这些患者的睡眠质量与认知功能相关，提示改善患者的睡眠质量有助于改善其认知功能。
