Sleep Psychosomatic Medicine Center, Taihe Hospital of Shiyan City, Hubei University of Medicine, 442000, China.
Biomed Res Int. 2022 May 14;2022:9709536. doi: 10.1155/2022/9709536. eCollection 2022.
To explore the relationship between sleep time, sleep quality, and emotional and cognitive function in the elderly.
A total of 150 elderly patients over 65 years old who were admitted to our hospital from February 2019 to April 2021 were divided into a normal cognitive function group (Mini-Mental State Examination (MMSE) score: illiteracy, >17; primary school, >20; and middle school and above, >24; = 86) and cognitive impairment group (MMSE score: illiteracy, ≤17; primary school, ≤20; and middle school or above, ≤24; = 64). The sleep quality was evaluated by the Pittsburgh Sleep Quality Index (PSQI), and anxiety and depression were evaluated by Hamilton anxiety scale (HAMA) and Hamilton depression scale (HAMD), respectively. The cognitive function between the two groups was compared via the Montreal Cognitive Assessment (MoCA) score, visual spatial execution, and attention. Pearson correlation analysis was used to analyze the correlation between sleep quality, sleep time, and emotional and cognitive function.
In the comparison of sleep quality between the two groups, the total score of PSQI, sleep quality, falling asleep time, sleep time, and sleep efficiency of patients with cognitive impairment were higher than those of patients with normal cognitive function ( < 0.05). There was no significant difference in the scores of hypnotic use and daytime dysfunction between the two groups, but the scores of nocturnal sleep disorders and ESS in the cognitive impairment group were significantly higher than those in the normal group ( > 0.05). Compared between the two groups, the MoCA score, visual spatial execution, and attention in the cognitive impairment group were significantly lower than those in the normal group, and the difference was statistically significant ( < 0.05). The delayed recall in the cognitive impairment group was significantly higher than that in the control group ( < 0.05). There was no significant difference in orientation, naming, language, and abstract ability between the two groups ( > 0.05). The scores of HAMA and HAMD in the cognitive impairment group were significantly higher than those in the normal group. Pearson correlation analysis was used to analyze the correlation between sleep therapy, sleep time, and the score of cognitive scale. The results showed that PSQI was negatively correlated with MoCA and MMSE, and ESS was negatively correlated with MoCA and MMSE. Pearson correlation analysis results indicated that PSQI was positively correlated with HAMA and HAMD, while ESS was negatively correlated with HAMA and HAMD.
The sleep quality and sleep time of elderly patients are positively correlated with their cognitive function. The worse the sleep quality is, the worse their cognitive function is and the more serious their anxiety and depression are. In the course of clinical therapeutics, more attention should be paid to the sleep quality of elderly.
探讨老年人睡眠时间、睡眠质量与情绪认知功能的关系。
选取 2019 年 2 月至 2021 年 4 月我院收治的 150 例年龄 65 岁以上的老年患者，分为正常认知功能组（简易精神状态检查量表（MMSE）评分：文盲，＞17；小学，＞20；中学及以上，＞24； = 86）和认知功能障碍组（MMSE 评分：文盲，≤17；小学，≤20；中学及以上，≤24； = 64）。采用匹兹堡睡眠质量指数（PSQI）评估睡眠质量，采用汉密尔顿焦虑量表（HAMA）和汉密尔顿抑郁量表（HAMD）分别评估焦虑和抑郁。通过蒙特利尔认知评估量表（MoCA）评分、视觉空间执行、注意力比较两组认知功能的差异。采用 Pearson 相关分析分析睡眠质量、睡眠时间与情绪认知功能的相关性。
两组患者睡眠质量比较，认知功能障碍组 PSQI 总分、睡眠质量、入睡时间、睡眠时间、睡眠效率均高于正常认知功能组（ < 0.05）。两组催眠药物使用和日间功能障碍评分无明显差异，但认知功能障碍组夜间睡眠障碍和 ESS 评分明显高于正常组（ > 0.05）。两组比较，认知功能障碍组 MoCA 评分、视觉空间执行、注意力明显低于正常组，差异有统计学意义（ < 0.05）。认知功能障碍组延迟回忆明显高于对照组（ < 0.05）。两组定向力、命名、语言、抽象能力比较无明显差异（ > 0.05）。认知功能障碍组 HAMA 和 HAMD 评分明显高于正常组。Pearson 相关分析显示，PSQI 与 MoCA 和 MMSE 呈负相关，ESS 与 MoCA 和 MMSE 呈负相关。Pearson 相关分析结果表明，PSQI 与 HAMA 和 HAMD 呈正相关，而 ESS 与 HAMA 和 HAMD 呈负相关。
老年患者的睡眠质量和睡眠时间与认知功能呈正相关。睡眠质量越差，认知功能越差，焦虑抑郁越严重。在临床治疗过程中，应更加关注老年患者的睡眠质量。
