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罗马尼亚髋部骨折的发病率及时间趋势:一项2008年至2018年的全国性研究

INCIDENCE AND TIME TREND OF HIP FRACTURES IN ROMANIA: A NATIONWIDE STUDY FROM 2008 TO 2018.

作者信息

Grigorie D, Sucaliuc A, Ciutan M, Vladescu C

机构信息

"C.I. Parhon" National Institute of Endocrinology, Bucharest, Romania.

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

Acta Endocrinol (Buchar). 2019 Oct-Dec;15(4):505-512. doi: 10.4183/aeb.2019.505.

DOI:10.4183/aeb.2019.505
PMID:32377249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7200111/
Abstract

BACKGROUND

Hip fractures are a major issue of public health as they are responsible for high morbidity, excess mortality and costs. There are differences in Europe and worldwide in the incidence rates of hip fractures and time trends, in the context of the population aging. Ten years ago, we characterized the incidence of hip fracture in Romania using data from the national hospital discharge register.

OBJECTIVE

This is the first Romanian study to assess the hip fracture incidence rates over a period of 11 years, between 2008 and 2018.

SUBJECTS AND METHODS

This analysis is a nationwide retrospective study on hospitals reporting primary DRG data on hip fracture, using a rigorous definition with both diagnostic and surgical procedure codes. The population aged 40+ was stratified in 5-year intervals and both the crude incidence rates and the adjusted incidence rates of hip fracture using standardization on age for the 2018 reference population were calculated in women and men.

RESULTS

From 2008 to 2018, the number of hip fractures rose by 53 % in women (from 7513 to 11512) and 22.4 % in men (from 4266 to 5220). Meanwhile, the Romanian population over 40 years increased by 12.5% in women and 14.2% in men. The crude incidence rate rose by 36.2% in women and 7.2% in men and the age-standardized incidence rates by 27.4% in women and 6% in men. These increases are mostly based on 85+ age populations' changes.

CONCLUSIONS

In Romania, the hip fractures incidence continues to grow throughout an 11-year-period, especially in women, representing an increasing burden for our society.

摘要

背景

髋部骨折是一个重大的公共卫生问题,因为它们会导致高发病率、额外死亡率和高昂成本。在人口老龄化的背景下,欧洲和全球髋部骨折的发病率及时间趋势存在差异。十年前,我们利用国家医院出院登记数据对罗马尼亚髋部骨折的发病率进行了描述。

目的

这是罗马尼亚第一项评估2008年至2018年11年间髋部骨折发病率的研究。

对象与方法

本分析是一项全国性的回顾性研究,针对报告髋部骨折初级诊断相关分组(DRG)数据的医院,采用严格的定义并结合诊断和手术操作代码。40岁及以上人群按5年间隔分层,计算了2018年参考人群中女性和男性髋部骨折的粗发病率和经年龄标准化后的发病率。

结果

从2008年到2018年,女性髋部骨折数量增加了53%(从7513例增至11512例),男性增加了22.4%(从4266例增至5220例)。与此同时,罗马尼亚40岁以上女性人口增加了12.5%,男性增加了14.2%。女性粗发病率上升了36.2%,男性上升了7.2%;年龄标准化发病率女性上升了27.4%,男性上升了6%。这些增长主要基于85岁及以上人群的变化。

结论

在罗马尼亚,髋部骨折发病率在11年期间持续上升,尤其是在女性中,这给我们的社会带来了日益沉重的负担。

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J Clin Med. 2019 Sep 18;8(9):1487. doi: 10.3390/jcm8091487.
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Secular trends in major osteoporotic fractures among 50+ adults in Denmark between 1995 and 2010.1995 年至 2010 年期间丹麦 50 岁以上成年人主要骨质疏松性骨折的长期趋势。
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The incidence of hip fracture and mortality rate after hip fracture in Korea: A nationwide population-based cohort study.韩国髋部骨折的发病率及髋部骨折后的死亡率:一项基于全国人口的队列研究。
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Performance of FRAX and FRAX-Based Treatment Thresholds in Women Aged 40 Years and Older: The Manitoba BMD Registry.40 岁及以上女性 FRAX 和基于 FRAX 的治疗阈值的性能:马尼托巴省 BMD 注册研究。
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