Garuti L, Ferranti A, Varoli L, Giovanninetti G, Brigidi P
Department of Pharmaceutical Science, University of Fermentation Chemistry, Faculty of Pharmacy, Bologna, Italy.
Pharmazie. 1988 Aug;43(8):535-6.
A short series of N-monosubstituted (aryl, aminoacyl, dipeptidyl)-2-(2-aminothiazol-4-yl)-(Z) -2-methoxyiminoacetamides was synthesized and tested for antimicrobial activity. A few members showed a somewhat interesting inhibitory action against Cryptococcus neoformans (MIC = 150 micrograms/ml).
合成了一系列短链的N-单取代（芳基、氨酰基、二肽基）-2-（2-氨基噻唑-4-基）-（Z）-2-甲氧基亚氨基乙酰胺，并测试了其抗菌活性。其中一些成员对新型隐球菌表现出了一定有趣的抑制作用（最低抑菌浓度=150微克/毫升）。
