正常年轻女性对氟哌啶醇的催乳素反应。

Prolactin responses to haloperidol in normal young women.

作者信息

Asnis G M, Sachar E J, Langer G, Tabrizi M A, Nathan R S, Halpern F S, Halbreich U

机构信息

Department of Psychiatry, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, New York 10467.

出版信息

Psychoneuroendocrinology. 1988;13(6):515-20. doi: 10.1016/0306-4530(88)90037-6.

DOI:10.1016/0306-4530(88)90037-6

PMID:3237947

Abstract

The prolactin (PRL) responses to intramuscular haloperidol (HPD) (0.5, 1.0, and 1.5 mg) were evaluated in six normal premenopausal women during the follicular and luteal phases of their menstrual cycles. These were compared to the PRL responses to these doses of HPD in normal young men. PRL responses to HPD did not differ between the follicular and luteal phases. The mean log-transformed PRL response to the lowest HPD dose (0.5 mg) in women was less than that in the men, but the women had greater PRL responses than the men to the higher haloperidol doses (1.0 mg and 1.5 mg).

摘要

在6名正常绝经前女性月经周期的卵泡期和黄体期，评估了她们对肌肉注射氟哌啶醇（HPD）（0.5、1.0和1.5毫克）的催乳素（PRL）反应。将这些反应与正常年轻男性对这些剂量HPD的PRL反应进行比较。卵泡期和黄体期之间，对HPD的PRL反应没有差异。女性对最低HPD剂量（0.5毫克）的平均对数转换PRL反应低于男性，但女性对较高氟哌啶醇剂量（1.0毫克和1.5毫克）的PRL反应比男性更大。