MMWR Morb Mortal Wkly Rep. 2020 May 8;69(18):545-550. doi: 10.15585/mmwr.mm6918e1.
SARS-CoV-2, the novel coronavirus that causes coronavirus disease 2019 (COVID-19), was first detected in the United States during January 2020 (1). Since then, >980,000 cases have been reported in the United States, including >55,000 associated deaths as of April 28, 2020 (2). Detailed data on demographic characteristics, underlying medical conditions, and clinical outcomes for persons hospitalized with COVID-19 are needed to inform prevention strategies and community-specific intervention messages. For this report, CDC, the Georgia Department of Public Health, and eight Georgia hospitals (seven in metropolitan Atlanta and one in southern Georgia) summarized medical record-abstracted data for hospitalized adult patients with laboratory-confirmed* COVID-19 who were admitted during March 2020. Among 305 hospitalized patients with COVID-19, 61.6% were aged <65 years, 50.5% were female, and 83.2% with known race/ethnicity were non-Hispanic black (black). Over a quarter of patients (26.2%) did not have conditions thought to put them at higher risk for severe disease, including being aged ≥65 years. The proportion of hospitalized patients who were black was higher than expected based on overall hospital admissions. In an adjusted time-to-event analysis, black patients were not more likely than were nonblack patients to receive invasive mechanical ventilation (IMV) or to die during hospitalization (hazard ratio [HR] = 0.63; 95% confidence interval [CI] = 0.35-1.13). Given the overrepresentation of black patients within this hospitalized cohort, it is important for public health officials to ensure that prevention activities prioritize communities and racial/ethnic groups most affected by COVID-19. Clinicians and public officials should be aware that all adults, regardless of underlying conditions or age, are at risk for serious illness from COVID-19.
SARS-CoV-2,即导致 2019 冠状病毒病(COVID-19)的新型冠状病毒,于 2020 年 1 月在美国首次被检测到(1)。自那时以来,美国已报告超过 98 万例病例,包括截至 2020 年 4 月 28 日的 55000 多例与 COVID-19 相关的死亡病例(2)。需要详细的数据来了解患有 COVID-19 的住院患者的人口统计学特征、潜在的医疗条件和临床结果,以告知预防策略和特定社区的干预信息。为此,美国疾病控制与预防中心(CDC)、佐治亚州公共卫生部以及佐治亚州的八家医院(亚特兰大都会区的七家医院和佐治亚州南部的一家医院)总结了 2020 年 3 月期间住院的实验室确诊* COVID-19 成年患者的医疗记录摘要数据。在 305 名患有 COVID-19 的住院患者中,61.6%的年龄<65 岁,50.5%为女性,已知种族/族裔的 83.2%为非西班牙裔黑人(黑人)。超过四分之一的患者(26.2%)没有被认为存在更高风险患严重疾病的情况,包括年龄≥65 岁。住院患者中黑人的比例高于根据总住院人数预期的比例。在调整后的生存时间分析中,黑人患者接受有创机械通气(IMV)或在住院期间死亡的可能性并不高于非黑人患者(危险比[HR] = 0.63;95%置信区间[CI] = 0.35-1.13)。鉴于该住院患者队列中黑人患者的代表性过高,公共卫生官员必须确保预防活动优先考虑受 COVID-19 影响最大的社区和种族/族裔群体。临床医生和公共官员应注意,所有成年人,无论其潜在疾病或年龄如何,都有患 COVID-19 严重疾病的风险。