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骨水平和组织水平种植体周围边缘性骨丧失:系统评价和荟萃分析。

Marginal bone loss around bone-level and tissue-level implants: A systematic review and meta-analysis.

机构信息

Department of Periodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

Research Center for Caries Prevention, Dentistry Research Institute, Department of Community Oral Health, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Ann Anat. 2020 Sep;231:151525. doi: 10.1016/j.aanat.2020.151525. Epub 2020 May 4.

Abstract

PURPOSE

To review the scientific evidence regarding the marginal bone loss around the tissue-level and bone-level implants.

METHODS

MEDLINE-PubMed and EMBASE databases were searched for the relevant English articles (up to February 2019) assessing the marginal bone loss (MBL) as the primary outcome. To be selected, studies were supposed to directly mention "tissue-level" and "bone-level" implants or implants with and without a smooth neck. Relevant data were extracted and meta-analysis was performed to evaluate the effect of implant neck design.

RESULTS

A total of 19 studies (10 clinical, and 9 RCT studies) were included for qualitative analysis. There was a vast heterogeneity between studies in terms of implant designs and study protocol. Out of 19 articles included, 11 studies reached to a statistically significant difference in MBL between the groups; however, the differences were not found to be clinically relevant. Bone-level implants with platform-switched abutments in most of the cases showed better marginal bone stability compared to tissue-level implants or bone-level implants with matching abutments. Seven RCTs with 12 months follow-up data were selected for meta-analysis (I=93%; heterogeneous), and the results showed less MBL around bone-level implants compared to tissue-level group (WMD=-0.21mm; 95% CI -0.42, 0.00; P=0.06).

CONCLUSION

The available data regarding comparison of MBL around bone-level and tissue-level implants are heterogeneous. Bone-level implants with platform switching may better preserve crestal bone.

摘要

目的

回顾关于组织水平和骨水平种植体周围边缘骨丢失的科学证据。

方法

检索 MEDLINE-PubMed 和 EMBASE 数据库中评估边缘骨丢失(MBL)作为主要结局的相关英文文章(截至 2019 年 2 月)。为了进行选择,研究应直接提及“组织水平”和“骨水平”种植体或带有和不带有光滑颈部的种植体。提取相关数据并进行荟萃分析,以评估种植体颈部设计的效果。

结果

共纳入 19 项研究(10 项临床研究和 9 项 RCT 研究)进行定性分析。在种植体设计和研究方案方面,研究之间存在很大的异质性。在纳入的 19 篇文章中,有 11 篇研究在 MBL 方面显示出组间存在统计学显著差异;然而,差异并未被认为具有临床相关性。在大多数情况下,具有平台转换基台的骨水平种植体与组织水平种植体或匹配基台的骨水平种植体相比,显示出更好的边缘骨稳定性。选择了 7 项具有 12 个月随访数据的 RCT 进行荟萃分析(I=93%;异质性),结果显示骨水平种植体周围的 MBL 少于组织水平组(WMD=-0.21mm;95%CI-0.42,0.00;P=0.06)。

结论

关于骨水平和组织水平种植体周围 MBL 比较的现有数据存在异质性。具有平台转换的骨水平种植体可能更好地保留牙槽嵴骨。

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