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Definitive Treatment of Femoral Shaft Fractures: Comparison between Anterograde Intramedullary Nailing and Monoaxial External Fixation.股骨干骨折的确定性治疗：顺行髓内钉固定与单轴外固定的比较
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Bone substitutes: a review of their characteristics, clinical use, and perspectives for large bone defects management.骨替代物：其特性、临床应用及大骨缺损治疗前景综述
J Tissue Eng. 2018 Jun 4;9:2041731418776819. doi: 10.1177/2041731418776819. eCollection 2018 Jan-Dec.
3
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Ortop Traumatol Rehabil. 2017 Apr 12;19(2):111-125. doi: 10.5604/15093492.1237999.
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Osteomyelitis.骨髓炎
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Outcome of distraction osteogenesis by ring fixator in infected, large bone defects of tibia.环形固定器治疗感染性胫骨大段骨缺损的牵张成骨结果
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Calcium Phosphates and Angiogenesis: Implications and Advances for Bone Regeneration.钙磷与血管生成：在骨再生方面的意义和进展。
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8
Two stage reconstruction versus bone transport in management of resistant infected tibial diaphyseal nonunion with a gap.两阶段重建与骨搬运治疗伴有骨缺损的难治性感染性胫骨干骨折不愈合的比较
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9
The treatment of infected tibial nonunion by bone transport using the Ilizarov external fixator and a systematic review of infected tibial nonunion treated by Ilizarov methods.采用伊利扎洛夫外固定器行骨搬运治疗感染性胫骨骨不连及对伊利扎洛夫方法治疗感染性胫骨骨不连的系统评价
Acta Orthop Belg. 2014 Sep;80(3):426-35.
10
Outcome of limb reconstruction system in open tibial diaphyseal fractures.肢体重建系统治疗开放性胫骨干骨折的疗效
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采用伊里扎洛夫技术治疗感染性胫骨骨不连：病例系列

Treatment of Infected Tibial Non-Unions with Ilizarov Technique: A Case Series.

作者信息

Testa Gianluca, Vescio Andrea, Aloj Domenico Costantino, Costa Danilo, Papotto Giacomo, Gurrieri Luca, Sessa Giuseppe, Pavone Vito

机构信息

Department of General Surgery and Medical Surgical Specialties, Section of Orthopaedics and Traumatology, AOU Policlinico-Vittorio Emanuele, University of Catania, 95123 Catania, Italy.

Department of Traumatology, PO Sant'Andrea, 13100 Vercelli, Italy.

出版信息

J Clin Med. 2020 May 5;9(5):1352. doi: 10.3390/jcm9051352.

DOI:10.3390/jcm9051352
PMID:32380709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7291197/
Abstract

BACKGROUND

The Ilizarov external fixation technique has been widely used for the treatment of long-bone infected non-unions. After surgical infected bone resection, to allow filling of the remaining bone gap, biomaterials with antibacterial properties could be used. The aim of this study was to report outcomes of infected tibial non-unions treated using the Ilizarov technique and antibacterial bioactive glass.

METHODS

Between April 2009 and December 2014, 26 patients with infected tibial non-unions were treated with the Ilizarov technique and possible use of the bioactive glass, S53P4. The Association for the Study and Application of Methods of Ilizarov (ASAMI) criteria, a clinical and radiographic evaluating tool, was used for assessing the sample.

RESULTS

The average age at the start of treatment was 51 years. The mean follow-up time was 113 weeks. According to the ASAMI Functional Scoring System, 10 excellent (38.5%) cases and 12 good (46.1%) values were recorded. According to the ASAMI Radiological System, they were excellent in 16 (61.5%) cases and good in nine (34.6%).

CONCLUSIONS

Treatment of infected tibial non-unions using the Ilizarov technique was effective in bone segment regeneration. To fill the remaining bone gap, additional bioactive glass S53P4 could be used, allowing a decrease in re-interventions and minimizing complications.

摘要

背景

伊里扎洛夫外固定技术已广泛应用于长骨感染性骨不连的治疗。手术切除感染骨后，可使用具有抗菌性能的生物材料来填充剩余的骨缺损。本研究的目的是报告使用伊里扎洛夫技术和抗菌生物活性玻璃治疗感染性胫骨骨不连的结果。

方法

2009年4月至2014年12月期间，26例感染性胫骨骨不连患者接受了伊里扎洛夫技术治疗，并可能使用了生物活性玻璃S53P4。使用伊里扎洛夫方法研究与应用协会（ASAMI）标准这一临床和影像学评估工具对样本进行评估。

结果

治疗开始时的平均年龄为51岁。平均随访时间为113周。根据ASAMI功能评分系统，记录到10例（38.5%）优秀病例和12例（46.1%）良好病例。根据ASAMI放射学系统，16例（61.5%）为优秀，9例（34.6%）为良好。

结论

使用伊里扎洛夫技术治疗感染性胫骨骨不连对骨段再生有效。为填充剩余的骨缺损，可使用额外的生物活性玻璃S53P4，从而减少再次干预并将并发症降至最低。